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Spats2l spermatogenesis associated, serine-rich 2-like [ Mus musculus (house mouse) ]

Gene ID: 67198, updated on 26-Sep-2022

Summary

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Official Symbol
Spats2lprovided by MGI
Official Full Name
spermatogenesis associated, serine-rich 2-likeprovided by MGI
Primary source
MGI:MGI:1914448
See related
Ensembl:ENSMUSG00000038305 AllianceGenome:MGI:1914448
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2810022L02Rik; A230104H11Rik
Summary
Predicted to be located in cytosol; nucleolus; and nucleoplasm. Predicted to be part of protein-containing complex. Predicted to be active in cytoplasm. Is expressed in several structures, including brain; cranium; foot mesenchyme; foregut; and genitourinary system. Orthologous to human SPATS2L (spermatogenesis associated serine rich 2 like). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in limb E14.5 (RPKM 12.7), CNS E18 (RPKM 5.8) and 22 other tissues See more
Orthologs
human all
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Genomic context

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See Spats2l in Genome Data Viewer
Location:
1; 1 C1.3
Exon count:
17
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (57813261..57987557)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (57774102..57948398)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA48 Neighboring gene predicted gene, 17929 Neighboring gene small nucleolar RNA U13 Neighboring gene potassium channel tetramerisation domain containing 18 Neighboring gene shugoshin 2A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Transcriptome analysis of mouse stem cells and early embryos. Sharov AA, et al. PLoS Biol, 2003 Dec. PMID 14691545, Free PMC Article
  2. Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics. Federspiel JD, et al. Mol Cell Proteomics, 2019 Aug 9. PMID 31040226, Free PMC Article
  3. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  4. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559
  5. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of protein-containing complex ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
SPATS2-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001164566.1 → NP_001158038.1  SPATS2-like protein isoform 2

    See identical proteins and their annotated locations for NP_001158038.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, uses an downstream translational start codon, and uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
    Source sequence(s)
    AC110735, AC112971, AK032169, BE335142, BY069430, BY634273, BY739337, CK624383, CN698528
    Consensus CDS
    CCDS48267.1
    UniProtKB/Swiss-Prot
    Q91WJ7
    Related
    ENSMUSP00000132975.2, ENSMUST00000169772.3
    Conserved Domains (1) summary
    pfam07139
    Location:59 → 368
    DUF1387; Protein of unknown function (DUF1387)

  2. NM_001368787.1 → NP_001355716.1  SPATS2-like protein isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC110735, AC112971, AC157804
    UniProtKB/Swiss-Prot
    Q8VC37
    Conserved Domains (1) summary
    pfam07139
    Location:59 → 368
    DUF1387; Protein of unknown function (DUF1387)

  3. NM_144882.4 → NP_659131.2  SPATS2-like protein isoform 1

    See identical proteins and their annotated locations for NP_659131.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (1).
    Source sequence(s)
    AC110735, AC157804, AK032169, BY317793, BY634273
    Consensus CDS
    CCDS35573.2
    UniProtKB/Swiss-Prot
    Q91WJ7
    UniProtKB/TrEMBL
    E9PVQ3
    Related
    ENSMUSP00000133054.2, ENSMUST00000167085.8
    Conserved Domains (1) summary
    pfam07139
    Location:79 → 388
    DUF1387; Protein of unknown function (DUF1387)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    57813261..57987557
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006496210.5 → XP_006496273.1  SPATS2-like protein isoform X2

    See identical proteins and their annotated locations for XP_006496273.1

    UniProtKB/TrEMBL
    E9PVQ3
    Conserved Domains (1) summary
    pfam07139
    Location:79 → 388
    DUF1387; Protein of unknown function (DUF1387)

  2. XM_017322123.2 → XP_017177612.1  SPATS2-like protein isoform X3

    Conserved Domains (1) summary
    pfam07139
    Location:79 → 387
    DUF1387; Protein of unknown function (DUF1387)

  3. XM_006496217.5 → XP_006496280.1  SPATS2-like protein isoform X5

    See identical proteins and their annotated locations for XP_006496280.1

    Conserved Domains (1) summary
    pfam07139
    Location:79 → 318
    DUF1387; Protein of unknown function (DUF1387)

  4. XM_006496211.5 → XP_006496274.1  SPATS2-like protein isoform X2

    See identical proteins and their annotated locations for XP_006496274.1

    UniProtKB/TrEMBL
    E9PVQ3
    Conserved Domains (1) summary
    pfam07139
    Location:79 → 388
    DUF1387; Protein of unknown function (DUF1387)

  5. XM_030242305.1 → XP_030098165.1  SPATS2-like protein isoform X3

    Conserved Domains (1) summary
    pfam07139
    Location:79 → 387
    DUF1387; Protein of unknown function (DUF1387)

  6. XM_036153073.1 → XP_036008966.1  SPATS2-like protein isoform X1

    Related
    ENSMUSP00000127598.2, ENSMUST00000170139.8
    Conserved Domains (1) summary
    pfam07139
    Location:59 → 368
    DUF1387; Protein of unknown function (DUF1387)

  7. XM_006496212.4 → XP_006496275.1  SPATS2-like protein isoform X2

    See identical proteins and their annotated locations for XP_006496275.1

    UniProtKB/TrEMBL
    E9PVQ3
    Conserved Domains (1) summary
    pfam07139
    Location:79 → 388
    DUF1387; Protein of unknown function (DUF1387)

  8. XM_006496218.5 → XP_006496281.1  SPATS2-like protein isoform X4

    See identical proteins and their annotated locations for XP_006496281.1

    UniProtKB/Swiss-Prot
    Q8VC37, Q91WJ7
    Conserved Domains (1) summary
    pfam07139
    Location:59 → 368
    DUF1387; Protein of unknown function (DUF1387)

  9. XM_006496216.5 → XP_006496279.1  SPATS2-like protein isoform X5

    See identical proteins and their annotated locations for XP_006496279.1

    Conserved Domains (1) summary
    pfam07139
    Location:79 → 318
    DUF1387; Protein of unknown function (DUF1387)

  10. XM_030242308.1 → XP_030098168.1  SPATS2-like protein isoform X6

    Related
    ENSMUSP00000132592.2, ENSMUST00000164302.8
    Conserved Domains (1) summary
    pfam07139
    Location:79 → 318
    DUF1387; Protein of unknown function (DUF1387)

  11. XM_017322122.3 → XP_017177611.1  SPATS2-like protein isoform X3

    Conserved Domains (1) summary
    pfam07139
    Location:79 → 387
    DUF1387; Protein of unknown function (DUF1387)

  12. XM_036153076.1 → XP_036008969.1  SPATS2-like protein isoform X2

    UniProtKB/TrEMBL
    E9PVQ3
    Conserved Domains (1) summary
    pfam07139
    Location:79 → 388
    DUF1387; Protein of unknown function (DUF1387)

  13. XM_036153087.1 → XP_036008980.1  SPATS2-like protein isoform X4

    UniProtKB/Swiss-Prot
    Q8VC37
    Conserved Domains (1) summary
    pfam07139
    Location:59 → 368
    DUF1387; Protein of unknown function (DUF1387)

  14. XM_006496215.5 → XP_006496278.1  SPATS2-like protein isoform X4

    See identical proteins and their annotated locations for XP_006496278.1

    UniProtKB/Swiss-Prot
    Q8VC37, Q91WJ7
    Conserved Domains (1) summary
    pfam07139
    Location:59 → 368
    DUF1387; Protein of unknown function (DUF1387)

  15. XM_030242309.2 → XP_030098169.1  SPATS2-like protein isoform X7

    Conserved Domains (1) summary
    pfam07139
    Location:59 → 298
    DUF1387; Protein of unknown function (DUF1387)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q91WJ7.2 GenPept UniProtKB/Swiss-Prot:Q91WJ7

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