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Pdzk1ip1 PDZK1 interacting protein 1 [ Mus musculus (house mouse) ]

Gene ID: 67182, updated on 12-Apr-2023

Summary

Official Symbol
Pdzk1ip1provided by MGI
Official Full Name
PDZK1 interacting protein 1provided by MGI
Primary source
MGI:MGI:1914432
See related
Ensembl:ENSMUSG00000028716 AllianceGenome:MGI:1914432
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Map17; 0610007F13Rik; 2700030M23Rik
Summary
Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including central nervous system; dorsal aorta; metanephros; naris; and retina. Orthologous to human PDZK1IP1 (PDZK1 interacting protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in kidney adult (RPKM 657.0), colon adult (RPKM 64.0) and 3 other tissues See more
Orthologs
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Genomic context

See Pdzk1ip1 in Genome Data Viewer
Location:
4; 4 D1
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2023_04 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (114945905..114951091)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (115088708..115093894)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 52674 Neighboring gene predicted gene, 33786 Neighboring gene T cell acute lymphocytic leukemia 1 Neighboring gene cytochrome P450, family 4, subfamily x, polypeptide 1 Neighboring gene cytochrome P450, family 4, subfamily x, polypeptide 1, opposite strand Neighboring gene cytochrome P450, family 4, subfamily a, polypeptide 28, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
PDZK1-interacting protein 1
Names
17 kDa membrane-associated protein
membrane-associated protein 17 (Map17)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001164557.1NP_001158029.1  PDZK1-interacting protein 1 isoform 1

    See identical proteins and their annotated locations for NP_001158029.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1).
    Source sequence(s)
    AK007936, AL670035, DV058382, EH108199
    Consensus CDS
    CCDS51272.1
    UniProtKB/Swiss-Prot
    Q9CQH0
    UniProtKB/TrEMBL
    G3UW41
    Related
    ENSMUSP00000128118.2, ENSMUST00000171877.8
    Conserved Domains (1) summary
    pfam15807
    Location:84181
    MAP17; Membrane-associated protein 117 kDa, PDZK1-interacting protein 1
  2. NM_001164558.1NP_001158030.1  PDZK1-interacting protein 1 isoform 2 precursor

    See identical proteins and their annotated locations for NP_001158030.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks a segment of the 5' UTR and 5' coding region, and uses a downstream translational start codon, compared to variant 1. The encoded isoform (2) is shorter at the N-terminus, compared to isoform 1. Both variants 2 and 3 encode the same isoform.
    Source sequence(s)
    AL645473, AL670035, DV057288, DV058382
    Consensus CDS
    CCDS18487.1
    UniProtKB/Swiss-Prot
    Q9CQH0
    Related
    ENSMUSP00000136049.2, ENSMUST00000177647.8
    Conserved Domains (1) summary
    pfam15807
    Location:6114
    MAP17; Membrane-associated protein 117 kDa, PDZK1-interacting protein 1
  3. NM_026018.3NP_080294.1  PDZK1-interacting protein 1 isoform 2 precursor

    See identical proteins and their annotated locations for NP_080294.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks a segment of the 5' UTR and 5' coding region, and uses a downstream translational start codon, compared to variant 1. The encoded isoform (2) is shorter at the N-terminus, compared to isoform 1. Both variants 2 and 3 encode the same isoform.
    Source sequence(s)
    AK008253, AL670035, DV058382
    Consensus CDS
    CCDS18487.1
    UniProtKB/Swiss-Prot
    Q9CQH0
    Related
    ENSMUSP00000102158.3, ENSMUST00000106548.9
    Conserved Domains (1) summary
    pfam15807
    Location:6114
    MAP17; Membrane-associated protein 117 kDa, PDZK1-interacting protein 1

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2023_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    114945905..114951091
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030253719.2XP_030109579.1  PDZK1-interacting protein 1 isoform X1

    UniProtKB/Swiss-Prot
    Q9CQH0
    Conserved Domains (1) summary
    pfam15807
    Location:6114
    MAP17; Membrane-associated protein 117 kDa, PDZK1-interacting protein 1