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Lpar6 lysophosphatidic acid receptor 6 [ Mus musculus (house mouse) ]

Gene ID: 67168, updated on 18-Jun-2024

Summary

Official Symbol
Lpar6provided by MGI
Official Full Name
lysophosphatidic acid receptor 6provided by MGI
Primary source
MGI:MGI:1914418
See related
Ensembl:ENSMUSG00000033446 AllianceGenome:MGI:1914418
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
P2y5; P2ry5; 2610302I02Rik
Summary
Predicted to enable lysophosphatidic acid receptor activity. Acts upstream of or within blastocyst hatching. Predicted to be located in plasma membrane. Predicted to be integral component of plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; immune system; and integumental system. Human ortholog(s) of this gene implicated in hypotrichosis. Orthologous to human LPAR6 (lysophosphatidic acid receptor 6). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See Lpar6 in Genome Data Viewer
Location:
14 D3; 14 38.75 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (73475331..73477798)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (73237891..73240358)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 Neighboring gene predicted gene, 52109 Neighboring gene STARR-seq mESC enhancer starr_37111 Neighboring gene STARR-seq mESC enhancer starr_37112 Neighboring gene VISTA enhancer mm1341 Neighboring gene microRNA 687 Neighboring gene RB transcriptional corepressor 1 Neighboring gene STARR-seq mESC enhancer starr_37114 Neighboring gene STARR-seq mESC enhancer starr_37116 Neighboring gene STARR-positive B cell enhancer ABC_E9900 Neighboring gene CapStarr-seq enhancer MGSCv37_chr14:73788957-73789140 Neighboring gene integral membrane protein 2B Neighboring gene STARR-positive B cell enhancer ABC_E7335 Neighboring gene STARR-seq mESC enhancer starr_37118 Neighboring gene STARR-seq mESC enhancer starr_37119 Neighboring gene predicted gene, 35450

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Targeted (5)  1 citation

Pathways from PubChem

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables lysophosphatidic acid receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
lysophosphatidic acid receptor 6
Names
LPA receptor 6
LPA-6
P2Y purinoceptor 5
oleoyl-L-alpha-lysophosphatidic acid receptor
purinergic receptor (family A group 5)
purinergic receptor 5
purinergic receptor P2Y, G-protein coupled, 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_175116.4NP_780325.1  lysophosphatidic acid receptor 6

    See identical proteins and their annotated locations for NP_780325.1

    Status: VALIDATED

    Source sequence(s)
    AC154718
    Consensus CDS
    CCDS27268.1
    UniProtKB/Swiss-Prot
    A6H6N5, Q3TEJ6, Q8BMC0
    Related
    ENSMUSP00000042327.7, ENSMUST00000044405.8
    Conserved Domains (2) summary
    pfam00001
    Location:35291
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:29142
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    73475331..73477798
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)