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Lipt2 lipoyl(octanoyl) transferase 2 (putative) [ Mus musculus (house mouse) ]

Gene ID: 67164, updated on 5-Jan-2023

Summary

Official Symbol
Lipt2provided by MGI
Official Full Name
lipoyl(octanoyl) transferase 2 (putative)provided by MGI
Primary source
MGI:MGI:1914414
See related
Ensembl:ENSMUSG00000030725 AllianceGenome:MGI:1914414
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2610209A20Rik
Summary
Predicted to enable ligase activity; lipoyl(octanoyl) transferase activity; and octanoyl transferase activity (acting on glycine-cleavage complex H protein). Predicted to be involved in positive regulation of oxygen metabolic process and protein lipoylation. Located in mitochondrion. Orthologous to human LIPT2 (lipoyl(octanoyl) transferase 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in ovary adult (RPKM 29.8), colon adult (RPKM 15.1) and 28 other tissues See more
Orthologs
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Genomic context

See Lipt2 in Genome Data Viewer
Location:
7; 7 E2
Exon count:
2
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (99808484..99810138)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (100159277..100160931)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene polymerase (DNA-directed), delta 3, accessory subunit Neighboring gene predicted gene, 34760 Neighboring gene predicted gene, 51452 Neighboring gene predicted gene, 39057 Neighboring gene predicted gene, 34821 Neighboring gene potassium voltage-gated channel, Isk-related subfamily, gene 3

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables acyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables ligase activity IEA
Inferred from Electronic Annotation
more info
 
enables lipoyl(octanoyl) transferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables octanoyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in positive regulation of oxygen metabolic process ISO
Inferred from Sequence Orthology
more info
 
involved_in protein lipoylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in protein lipoylation ISO
Inferred from Sequence Orthology
more info
 
involved_in protein modification process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
putative lipoyltransferase 2, mitochondrial
Names
lipoate-protein ligase B
lipoyl/octanoyl transferase
octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase
putative octanoyltransferase, mitochondrial
NP_080286.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_026010.2NP_080286.2  putative lipoyltransferase 2, mitochondrial

    See identical proteins and their annotated locations for NP_080286.2

    Status: VALIDATED

    Source sequence(s)
    AK008917, BC115472, BE648757
    Consensus CDS
    CCDS21494.1
    UniProtKB/Swiss-Prot
    Q9CVA5, Q9D009
    Related
    ENSMUSP00000032967.4, ENSMUST00000032967.4
    Conserved Domains (1) summary
    cl14057
    Location:1231
    BPL_LplA_LipB; Biotin/lipoate A/B protein ligase family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    99808484..99810138
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)