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Eef1g eukaryotic translation elongation factor 1 gamma [ Mus musculus (house mouse) ]

Gene ID: 67160, updated on 8-Jan-2023

Summary

Official Symbol
Eef1gprovided by MGI
Official Full Name
eukaryotic translation elongation factor 1 gammaprovided by MGI
Primary source
MGI:MGI:1914410
See related
Ensembl:ENSMUSG00000071644 AllianceGenome:MGI:1914410
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
EF1G; 2610301D06Rik
Summary
Predicted to enable translation elongation factor activity. Predicted to be involved in translational elongation. Predicted to act upstream of or within translation. Predicted to be active in cytoplasm and nucleus. Predicted to colocalize with endoplasmic reticulum. Is expressed in 2nd branchial arch; 3rd branchial pouch; and early conceptus. Orthologous to human EEF1G (eukaryotic translation elongation factor 1 gamma). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 183.6), testis adult (RPKM 170.4) and 28 other tissues See more
Orthologs
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Genomic context

See Eef1g in Genome Data Viewer
Location:
19; 19 A
Exon count:
10
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (8944405..8955544)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (8967041..8978180)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene predicted gene 10353 Neighboring gene metastasis-associated gene family, member 2 Neighboring gene terminal uridylyl transferase 1, U6 snRNA-specific Neighboring gene AHNAK nucleoprotein (desmoyokin) Neighboring gene secretoglobin, family 1A, member 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC103354, MGC144723, MGC144724

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables translation elongation factor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in glutathione metabolic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within translation IEA
Inferred from Electronic Annotation
more info
 
involved_in translational elongation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
colocalizes_with endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
elongation factor 1-gamma
Names
EF-1-gamma
eEF-1B gamma

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_026007.4NP_080283.3  elongation factor 1-gamma

    See identical proteins and their annotated locations for NP_080283.3

    Status: VALIDATED

    Source sequence(s)
    AK145519
    Consensus CDS
    CCDS29563.1
    UniProtKB/Swiss-Prot
    Q9D004, Q9D8N0
    UniProtKB/TrEMBL
    A0A8C6IHR1, Q4FZK2
    Related
    ENSMUSP00000093955.5, ENSMUST00000052248.8
    Conserved Domains (5) summary
    cd03181
    Location:91213
    GST_C_EF1Bgamma_like; Glutathione S-transferase C-terminal-like, alpha helical domain of the Gamma subunit of Elongation Factor 1B and similar proteins
    COG0625
    Location:5202
    GstA; Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]
    cd03044
    Location:482
    GST_N_EF1Bgamma; GST_N family, Gamma subunit of Elongation Factor 1B (EFB1gamma) subfamily; EF1Bgamma is part of the eukaryotic translation elongation factor-1 (EF1) complex which plays a central role in the elongation cycle during protein biosynthesis. EF1 consists of ...
    pfam00647
    Location:275381
    EF1G; Elongation factor 1 gamma, conserved domain
    cl15270
    Location:211265
    FinO_conjug_rep; FinO bacterial conjugation repressor domain; the basic protein FinO is part of the the two component FinOP system which is responsible for repressing bacterial conjugation; the FinOP system represses the transfer (tra) operon of the F-plasmid which ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    8944405..8955544
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)