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Zbtb8os zinc finger and BTB domain containing 8 opposite strand [ Mus musculus (house mouse) ]

Gene ID: 67106, updated on 26-Sep-2022

Summary

Official Symbol
Zbtb8osprovided by MGI
Official Full Name
zinc finger and BTB domain containing 8 opposite strandprovided by MGI
Primary source
MGI:MGI:1914356
See related
Ensembl:ENSMUSG00000057572 AllianceGenome:MGI:1914356
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Arch; Archm; 2010001H09Rik; 2310028N13Rik
Summary
Predicted to enable metal ion binding activity. Predicted to be involved in tRNA splicing, via endonucleolytic cleavage and ligation. Predicted to act upstream of or within tRNA processing. Predicted to be part of tRNA-splicing ligase complex. Is expressed in brain and embryo. Orthologous to human ZBTB8OS (zinc finger and BTB domain containing 8 opposite strand). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in placenta adult (RPKM 10.5), CNS E11.5 (RPKM 8.2) and 28 other tissues See more
Orthologs
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Genomic context

See Zbtb8os in Genome Data Viewer
Location:
4; 4 D2.2
Exon count:
7
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (129229325..129243664)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (129335532..129349871)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene expressed sequence C77080 Neighboring gene predicted gene 12976 Neighboring gene syncoilin Neighboring gene retinoblastoma binding protein 4, chromatin remodeling factor Neighboring gene zinc finger and BTB domain containing 8a Neighboring gene RIKEN cDNA C330020E22 gene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within tRNA processing IEA
Inferred from Electronic Annotation
more info
 
involved_in tRNA splicing, via endonucleolytic cleavage and ligation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in tRNA splicing, via endonucleolytic cleavage and ligation ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
part_of tRNA-splicing ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of tRNA-splicing ligase complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
protein archease
Names
archease (Arch)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025970.4NP_080246.1  protein archease

    See identical proteins and their annotated locations for NP_080246.1

    Status: VALIDATED

    Source sequence(s)
    AL607123
    Consensus CDS
    CCDS18689.1
    UniProtKB/Swiss-Prot
    Q505B7
    UniProtKB/TrEMBL
    B2KGA7
    Related
    ENSMUSP00000120925.2, ENSMUST00000141235.8
    Conserved Domains (1) summary
    pfam01951
    Location:31167
    Archease; Archease protein family (MTH1598/TM1083)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    129229325..129243664
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006503304.5XP_006503367.1  protein archease isoform X1

    See identical proteins and their annotated locations for XP_006503367.1

    UniProtKB/TrEMBL
    A0A6P7R541
    Conserved Domains (1) summary
    pfam01951
    Location:1110
    Archease; Archease protein family (MTH1598/TM1083)
  2. XM_017320361.3XP_017175850.1  protein archease isoform X2

    UniProtKB/TrEMBL
    A0A6P5PNC9
    Related
    ENSMUSP00000113004.2, ENSMUST00000119480.2
    Conserved Domains (1) summary
    pfam01951
    Location:43121
    Archease; Archease protein family (MTH1598/TM1083)