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SPRR2F small proline rich protein 2F [ Homo sapiens (human) ]

Gene ID: 6705, updated on 21-Dec-2019

Summary

Official Symbol
SPRR2Fprovided by HGNC
Official Full Name
small proline rich protein 2Fprovided by HGNC
Primary source
HGNC:HGNC:11266
See related
Ensembl:ENSG00000244094 MIM:617589
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Biased expression in esophagus (RPKM 38.5) and ovary (RPKM 21.7) See more
Orthologs

Genomic context

See SPRR2F in Genome Data Viewer
Location:
1q21.3
Exon count:
3
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (153112121..153119460, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (153084612..153085989, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene small proline rich protein 2B Neighboring gene small proline rich protein 2E Neighboring gene small proline rich protein 2C (pseudogene) Neighboring gene small proline rich protein 2G Neighboring gene uncharacterized LOC101928009

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

HIV-1 interactions

Protein interactions

Protein Gene Interaction Pubs
Envelope transmembrane glycoprotein gp41 env A synthetic peptide corresponding to the immunosuppressive domain (amino acids 574-592) of HIV-1 gp41 upregulates the expression of small proline-rich protein 2F (SPRR2F) in peptide-treated PBMCs PubMed

Go to the HIV-1, Human Interaction Database

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Process Evidence Code Pubs
cornification TAS
Traceable Author Statement
more info
 
epidermis development NAS
Non-traceable Author Statement
more info
PubMed 
keratinocyte differentiation NAS
Non-traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
cornified envelope NAS
Non-traceable Author Statement
more info
PubMed 
cornified envelope TAS
Traceable Author Statement
more info
 
cytosol TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
small proline-rich protein 2F
Names
SPR-2F

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001014450.3NP_001014450.1  small proline-rich protein 2F

    See identical proteins and their annotated locations for NP_001014450.1

    Status: VALIDATED

    Source sequence(s)
    AF333956, AI051688, AL139417
    Consensus CDS
    CCDS30867.1
    UniProtKB/Swiss-Prot
    Q96RM1
    Related
    ENSP00000418193.1, ENST00000468739.2

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    153112121..153119460 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017002176.1XP_016857665.1  small proline-rich protein 2F isoform X1

    UniProtKB/Swiss-Prot
    Q96RM1
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