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Actr6 ARP6 actin-related protein 6 [ Mus musculus (house mouse) ]

Gene ID: 67019, updated on 8-Dec-2022

Summary

Official Symbol
Actr6provided by MGI
Official Full Name
ARP6 actin-related protein 6provided by MGI
Primary source
MGI:MGI:1914269
See related
Ensembl:ENSMUSG00000019948 AllianceGenome:MGI:1914269
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Arp6; ArpX; CDA12; 2010200J04Rik
Summary
Predicted to enable nucleosome binding activity. Predicted to be involved in histone exchange. Predicted to be located in cytoplasm; cytoskeleton; and nucleus. Predicted to be part of Swr1 complex. Is expressed in ovary. Orthologous to human ACTR6 (actin related protein 6). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in CNS E18 (RPKM 7.5), CNS E14 (RPKM 6.0) and 20 other tissues See more
Orthologs
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Genomic context

See Actr6 in Genome Data Viewer
Location:
10; 10 C2
Exon count:
11
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (89547828..89568184, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (89711966..89732319, complement)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene SCY1-like 2 (S. cerevisiae) Neighboring gene RIKEN cDNA 1500026H17 gene Neighboring gene predicted gene, 30963 Neighboring gene bridge-like lipid transfer protein family member 3B Neighboring gene predicted gene, 31090

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables nucleosome binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in chromatin remodeling IEA
Inferred from Electronic Annotation
more info
 
involved_in nucleolus organization ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of DNA-templated transcription NAS
Non-traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
part_of Swr1 complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
 
part_of nucleosome NAS
Non-traceable Author Statement
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
actin-related protein 6
Names
ARP6 actin-related protein 6 homolog
mArp6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001359468.1NP_001346397.1  actin-related protein 6 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC130216, AK008409, BE861871, CJ221252
    Conserved Domains (1) summary
    smart00268
    Location:1286
    ACTIN; Actin
  2. NM_001359469.1NP_001346398.1  actin-related protein 6 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC130216, AK008409, CJ221252
    Conserved Domains (1) summary
    cl17037
    Location:1199
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily
  3. NM_025914.3NP_080190.1  actin-related protein 6 isoform 1

    See identical proteins and their annotated locations for NP_080190.1

    Status: VALIDATED

    Source sequence(s)
    AK008409, CJ221252
    Consensus CDS
    CCDS24118.1
    UniProtKB/Swiss-Prot
    Q9D864
    UniProtKB/TrEMBL
    A0A0R4J009
    Related
    ENSMUSP00000020109.4, ENSMUST00000020109.5
    Conserved Domains (2) summary
    smart00268
    Location:2394
    ACTIN; Actin
    COG5277
    Location:2393
    COG5277; Actin-related protein [Cytoskeleton]

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    89547828..89568184 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006513965.3XP_006514028.1  actin-related protein 6 isoform X1

    See identical proteins and their annotated locations for XP_006514028.1

    Conserved Domains (1) summary
    smart00268
    Location:10312
    ACTIN; Actin
  2. XM_006513966.4XP_006514029.1  actin-related protein 6 isoform X1

    See identical proteins and their annotated locations for XP_006514029.1

    Conserved Domains (1) summary
    smart00268
    Location:10312
    ACTIN; Actin
  3. XM_011243532.3XP_011241834.1  actin-related protein 6 isoform X2

    Conserved Domains (1) summary
    smart00268
    Location:1286
    ACTIN; Actin
  4. XM_006513967.4XP_006514030.1  actin-related protein 6 isoform X3

    Conserved Domains (1) summary
    cl17037
    Location:1199
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily
  5. XM_030245223.1XP_030101083.1  actin-related protein 6 isoform X2

    Conserved Domains (1) summary
    smart00268
    Location:1286
    ACTIN; Actin
  6. XM_036155958.1XP_036011851.1  actin-related protein 6 isoform X3

    Conserved Domains (1) summary
    cl17037
    Location:1199
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily
  7. XM_030245224.1XP_030101084.1  actin-related protein 6 isoform X3

    Conserved Domains (1) summary
    cl17037
    Location:1199
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily