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Cisd2 CDGSH iron sulfur domain 2 [ Mus musculus (house mouse) ]

Gene ID: 67006, updated on 30-Apr-2019

Summary

Official Symbol
Cisd2provided by MGI
Official Full Name
CDGSH iron sulfur domain 2provided by MGI
Primary source
MGI:MGI:1914256
See related
Ensembl:ENSMUSG00000028165
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Zcd2; Naf-1; Miner1; Noxp70; AI848398; 1500009M05Rik; 1500026J14Rik; 1500031D15Rik; B630006A20Rik
Expression
Ubiquitous expression in adrenal adult (RPKM 18.0), stomach adult (RPKM 11.7) and 28 other tissues See more
Orthologs

Genomic context

See Cisd2 in Genome Data Viewer
Location:
3; 3 G3
Exon count:
4
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 3 NC_000069.6 (135406412..135424075, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (135069376..135086397, complement)

Chromosome 3 - NC_000069.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 46826 Neighboring gene solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2 Neighboring gene solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1 Neighboring gene RIKEN cDNA 4930539J05 gene Neighboring gene ubiquitin-conjugating enzyme E2D 3 Neighboring gene predicted gene, 30992

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
2 iron, 2 sulfur cluster binding ISO
Inferred from Sequence Orthology
more info
 
iron-sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
autophagy IEA
Inferred from Electronic Annotation
more info
 
autophagy of mitochondrion IMP
Inferred from Mutant Phenotype
more info
PubMed 
multicellular organism aging IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of autophagy ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
PubMed 
endoplasmic reticulum membrane IDA
Inferred from Direct Assay
more info
PubMed 
endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
intracellular membrane-bounded organelle IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
mitochondrial outer membrane IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion IEA
Inferred from Electronic Annotation
more info
 
perinuclear endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
perinuclear region of cytoplasm ISO
Inferred from Sequence Orthology
more info
PubMed 
protein-containing complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
CDGSH iron-sulfur domain-containing protein 2
Names
mitoNEET-related 1 protein
nervous system over-expressed protein 70
nervous system overexpressed protein 70
nutrient-deprivation autophagy factor-1
zinc finger, CDGSH-type domain 2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025902.3NP_080178.1  CDGSH iron-sulfur domain-containing protein 2

    See identical proteins and their annotated locations for NP_080178.1

    Status: VALIDATED

    Source sequence(s)
    AC156618, BE944243
    Consensus CDS
    CCDS17856.1
    UniProtKB/Swiss-Prot
    Q9CQB5
    Related
    ENSMUSP00000029815.7, ENSMUST00000029815.7
    Conserved Domains (2) summary
    smart00704
    Location:81119
    ZnF_CDGSH; CDGSH-type zinc finger. Function unknown
    pfam10660
    Location:366
    MitoNEET_N; Iron-containing outer mitochondrial membrane protein N-terminus

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000069.6 Reference GRCm38.p4 C57BL/6J

    Range
    135406412..135424075 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006501918.3XP_006501981.1  CDGSH iron-sulfur domain-containing protein 2 isoform X1

    See identical proteins and their annotated locations for XP_006501981.1

    UniProtKB/Swiss-Prot
    Q9CQB5
    Conserved Domains (2) summary
    smart00704
    Location:81119
    ZnF_CDGSH; CDGSH-type zinc finger. Function unknown
    pfam10660
    Location:366
    MitoNEET_N; Iron-containing outer mitochondrial membrane protein N-terminus
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