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Cep19 centrosomal protein 19 [ Mus musculus (house mouse) ]

Gene ID: 66994, updated on 8-May-2024

Summary

Official Symbol
Cep19provided by MGI
Official Full Name
centrosomal protein 19provided by MGI
Primary source
MGI:MGI:1914244
See related
Ensembl:ENSMUSG00000035790 AllianceGenome:MGI:1914244
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1500031L02Rik
Summary
Predicted to be involved in microtubule anchoring at centrosome and vesicle targeting, trans-Golgi to periciliary membrane compartment. Predicted to act upstream of or within cell projection organization. Predicted to be located in cilium. Predicted to be active in microtubule cytoskeleton. Is expressed in axial skeleton; lower jaw; and lower jaw incisor. Orthologous to human CEP19 (centrosomal protein 19). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in cortex adult (RPKM 13.3), frontal lobe adult (RPKM 12.9) and 28 other tissues See more
Orthologs
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Genomic context

See Cep19 in Genome Data Viewer
Location:
16 B2; 16 22.4 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (31918618..31926875)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (32099789..32108068)

Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene p21 (RAC1) activated kinase 2 Neighboring gene predicted gene, 26419 Neighboring gene STARR-positive B cell enhancer ABC_E7439 Neighboring gene STARR-positive B cell enhancer ABC_E4164 Neighboring gene phosphatidylinositol glycan anchor biosynthesis, class X Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:32107830-32107983 Neighboring gene STARR-positive B cell enhancer ABC_E4165 Neighboring gene STARR-seq mESC enhancer starr_40643 Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:32130316-32130510 Neighboring gene negative regulator of reactive oxygen species Neighboring gene STARR-positive B cell enhancer ABC_E7441 Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:32177054-32177400 Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:32177409-32177592 Neighboring gene brain expressed family member 6

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Targeted (4)  1 citation

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within cell projection organization IEA
Inferred from Electronic Annotation
more info
 
involved_in cilium assembly ISO
Inferred from Sequence Orthology
more info
 
involved_in microtubule anchoring at centrosome IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in microtubule anchoring at centrosome ISO
Inferred from Sequence Orthology
more info
 
involved_in vesicle targeting, trans-Golgi to periciliary membrane compartment IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in vesicle targeting, trans-Golgi to periciliary membrane compartment ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
is_active_in centriole IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in centriole ISO
Inferred from Sequence Orthology
more info
 
is_active_in centrosome IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in centrosome ISO
Inferred from Sequence Orthology
more info
 
is_active_in ciliary basal body IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in ciliary basal body ISO
Inferred from Sequence Orthology
more info
 
located_in cilium ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in spindle pole IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in spindle pole ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
centrosomal protein of 19 kDa

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001416014.1NP_001402943.1  centrosomal protein of 19 kDa

    Status: VALIDATED

    Source sequence(s)
    AC135962
    UniProtKB/Swiss-Prot
    Q9CQA8
  2. NM_025892.4NP_080168.1  centrosomal protein of 19 kDa

    See identical proteins and their annotated locations for NP_080168.1

    Status: VALIDATED

    Source sequence(s)
    AC135962
    Consensus CDS
    CCDS28114.1
    UniProtKB/Swiss-Prot
    Q9CQA8
    Related
    ENSMUSP00000110822.3, ENSMUST00000115168.9
    Conserved Domains (1) summary
    pfam14933
    Location:6156
    CEP19; CEP19-like protein

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000082.7 Reference GRCm39 C57BL/6J

    Range
    31918618..31926875
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)