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Ssbp2 single-stranded DNA binding protein 2 [ Mus musculus (house mouse) ]

Gene ID: 66970, updated on 8-Feb-2024

Summary

Official Symbol
Ssbp2provided by MGI
Official Full Name
single-stranded DNA binding protein 2provided by MGI
Primary source
MGI:MGI:1914220
See related
Ensembl:ENSMUSG00000003992 AllianceGenome:MGI:1914220
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
SSDP2; Hspc116; 1500004K09Rik; 2310079I02Rik; 9330163K02Rik; A830008M03Rik
Summary
Predicted to enable single-stranded DNA binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Is expressed in several structures, including adipose tissue; alimentary system; central nervous system; genitourinary system; and limb. Orthologous to human SSBP2 (single stranded DNA binding protein 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in CNS E18 (RPKM 14.2), whole brain E14.5 (RPKM 8.6) and 18 other tissues See more
Orthologs
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Genomic context

See Ssbp2 in Genome Data Viewer
Location:
13 C3; 13 47.43 cM
Exon count:
24
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (91608449..91854299)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (91460305..91706175)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 41014 Neighboring gene heterogeneous nuclear ribonucleoprotein K pseudogene Neighboring gene RIKEN cDNA A830009L08 gene Neighboring gene STARR-seq mESC enhancer starr_35251 Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:91510584-91510802 Neighboring gene STARR-seq mESC enhancer starr_35253 Neighboring gene STARR-positive B cell enhancer mm9_chr13:91600311-91600612 Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:91680694-91680899 Neighboring gene predicted gene, 41016 Neighboring gene STARR-positive B cell enhancer mm9_chr13:91775680-91775980 Neighboring gene STARR-positive B cell enhancer mm9_chr13:91776398-91776699 Neighboring gene STARR-seq mESC enhancer starr_35255 Neighboring gene RIKEN cDNA 4833422C13 gene Neighboring gene predicted gene, 22778 Neighboring gene STARR-seq mESC enhancer starr_35256 Neighboring gene acyl-CoA thioesterase 12

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables single-stranded DNA binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in positive regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
single-stranded DNA-binding protein 2
Names
sequence-specific single-stranded-DNA-binding protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001360775.2NP_001347704.1  single-stranded DNA-binding protein 2 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC154320, CT009700
    Conserved Domains (2) summary
    smart00667
    Location:1945
    LisH; Lissencephaly type-1-like homology motif
    pfam04503
    Location:83346
    SSDP; Single-stranded DNA binding protein, SSDP
  2. NM_001360776.2NP_001347705.1  single-stranded DNA-binding protein 2 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC154320, CT009700
    Conserved Domains (2) summary
    smart00667
    Location:1945
    LisH; Lissencephaly type-1-like homology motif
    pfam04503
    Location:92316
    SSDP; Single-stranded DNA binding protein, SSDP
  3. NM_024186.6NP_077148.1  single-stranded DNA-binding protein 2 isoform 1

    See identical proteins and their annotated locations for NP_077148.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) lacks an alternate in-frame exon in the 5' coding region, compared to variant 2. The resulting isoform (1) lacks an internal segment, compared to isoform 2.
    Source sequence(s)
    AC154320, CT009700
    Consensus CDS
    CCDS26676.1
    UniProtKB/Swiss-Prot
    Q9CYZ8
    Related
    ENSMUSP00000037115.9, ENSMUST00000042122.15
    Conserved Domains (2) summary
    smart00667
    Location:1945
    LisH; Lissencephaly type-1-like homology motif
    pfam04503
    Location:92308
    SSDP; Single-stranded DNA binding protein, SSDP
  4. NM_024272.5NP_077234.2  single-stranded DNA-binding protein 2 isoform 2

    See identical proteins and their annotated locations for NP_077234.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) represents the longest transcript and encodes isoform 2.
    Source sequence(s)
    AC154320, CT009700
    Consensus CDS
    CCDS26677.1
    UniProtKB/Swiss-Prot
    B1B188, Q99LX9, Q9CYZ8
    UniProtKB/TrEMBL
    Q540I3
    Related
    ENSMUSP00000004094.9, ENSMUST00000004094.15
    Conserved Domains (2) summary
    smart00667
    Location:1945
    LisH; Lissencephaly type-1-like homology motif
    pfam04503
    Location:83338
    SSDP; Single-stranded DNA binding protein, SSDP

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    91608449..91854299
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030247373.2XP_030103233.1  single-stranded DNA-binding protein 2 isoform X12

    Conserved Domains (1) summary
    pfam04503
    Location:1232
    SSDP; Single-stranded DNA binding protein, SSDP
  2. XM_030247371.2XP_030103231.1  single-stranded DNA-binding protein 2 isoform X11

    Conserved Domains (1) summary
    pfam04503
    Location:1240
    SSDP; Single-stranded DNA binding protein, SSDP
  3. XM_030247377.2XP_030103237.1  single-stranded DNA-binding protein 2 isoform X14

    Conserved Domains (1) summary
    pfam04503
    Location:17212
    SSDP; Single-stranded DNA binding protein, SSDP
  4. XM_030247376.2XP_030103236.1  single-stranded DNA-binding protein 2 isoform X13

    Conserved Domains (1) summary
    pfam04503
    Location:17220
    SSDP; Single-stranded DNA binding protein, SSDP
  5. XM_006517334.4XP_006517397.1  single-stranded DNA-binding protein 2 isoform X8

    Conserved Domains (1) summary
    pfam04503
    Location:38301
    SSDP; Single-stranded DNA binding protein, SSDP
  6. XM_030247368.2XP_030103228.1  single-stranded DNA-binding protein 2 isoform X10

    Conserved Domains (1) summary
    pfam04503
    Location:47271
    SSDP; Single-stranded DNA binding protein, SSDP
  7. XM_036158126.1XP_036014019.1  single-stranded DNA-binding protein 2 isoform X7

    Conserved Domains (1) summary
    pfam04503
    Location:64319
    SSDP; Single-stranded DNA binding protein, SSDP
  8. XM_030247369.2XP_030103229.1  single-stranded DNA-binding protein 2 isoform X11

    Conserved Domains (1) summary
    pfam04503
    Location:1240
    SSDP; Single-stranded DNA binding protein, SSDP
  9. XM_030247372.2XP_030103232.1  single-stranded DNA-binding protein 2 isoform X11

    Conserved Domains (1) summary
    pfam04503
    Location:1240
    SSDP; Single-stranded DNA binding protein, SSDP
  10. XM_036158129.1XP_036014022.1  single-stranded DNA-binding protein 2 isoform X13

    Conserved Domains (1) summary
    pfam04503
    Location:17220
    SSDP; Single-stranded DNA binding protein, SSDP
  11. XM_030247375.2XP_030103235.1  single-stranded DNA-binding protein 2 isoform X12

    Conserved Domains (1) summary
    pfam04503
    Location:1232
    SSDP; Single-stranded DNA binding protein, SSDP
  12. XM_030247378.2XP_030103238.1  single-stranded DNA-binding protein 2 isoform X14

    Conserved Domains (1) summary
    pfam04503
    Location:17212
    SSDP; Single-stranded DNA binding protein, SSDP
  13. XM_030247367.2XP_030103227.1  single-stranded DNA-binding protein 2 isoform X9

    Conserved Domains (1) summary
    pfam04503
    Location:73289
    SSDP; Single-stranded DNA binding protein, SSDP
  14. XM_011244554.2XP_011242856.1  single-stranded DNA-binding protein 2 isoform X6

    Conserved Domains (1) summary
    pfam04503
    Location:64327
    SSDP; Single-stranded DNA binding protein, SSDP
  15. XM_036158130.1XP_036014023.1  single-stranded DNA-binding protein 2 isoform X14

    Conserved Domains (1) summary
    pfam04503
    Location:17212
    SSDP; Single-stranded DNA binding protein, SSDP
  16. XM_030247374.1XP_030103234.1  single-stranded DNA-binding protein 2 isoform X12

    Conserved Domains (1) summary
    pfam04503
    Location:1232
    SSDP; Single-stranded DNA binding protein, SSDP
  17. XM_036158127.1XP_036014020.1  single-stranded DNA-binding protein 2 isoform X11

    Conserved Domains (1) summary
    pfam04503
    Location:1240
    SSDP; Single-stranded DNA binding protein, SSDP
  18. XM_036158128.1XP_036014021.1  single-stranded DNA-binding protein 2 isoform X13

    Conserved Domains (1) summary
    pfam04503
    Location:17220
    SSDP; Single-stranded DNA binding protein, SSDP
  19. XM_036158131.1XP_036014024.1  single-stranded DNA-binding protein 2 isoform X14

    Conserved Domains (1) summary
    pfam04503
    Location:17212
    SSDP; Single-stranded DNA binding protein, SSDP
  20. XM_030247370.2XP_030103230.1  single-stranded DNA-binding protein 2 isoform X11

    Conserved Domains (1) summary
    pfam04503
    Location:1240
    SSDP; Single-stranded DNA binding protein, SSDP
  21. XM_036158125.1XP_036014018.1  single-stranded DNA-binding protein 2 isoform X3

    Conserved Domains (1) summary
    pfam04503
    Location:103337
    SSDP; Single-stranded DNA binding protein, SSDP
  22. XM_006517328.5XP_006517391.1  single-stranded DNA-binding protein 2 isoform X1

    Conserved Domains (1) summary
    pfam04503
    Location:103366
    SSDP; Single-stranded DNA binding protein, SSDP
  23. XM_006517329.4XP_006517392.1  single-stranded DNA-binding protein 2 isoform X2

    Conserved Domains (1) summary
    pfam04503
    Location:103358
    SSDP; Single-stranded DNA binding protein, SSDP
  24. XM_006517332.5XP_006517395.1  single-stranded DNA-binding protein 2 isoform X5

    Conserved Domains (1) summary
    pfam04503
    Location:112328
    SSDP; Single-stranded DNA binding protein, SSDP
  25. XM_011244553.4XP_011242855.1  single-stranded DNA-binding protein 2 isoform X4

    Conserved Domains (1) summary
    pfam04503
    Location:112336
    SSDP; Single-stranded DNA binding protein, SSDP

RNA

  1. XR_003950464.2 RNA Sequence

  2. XR_004938052.1 RNA Sequence

  3. XR_003950466.2 RNA Sequence

  4. XR_003950463.2 RNA Sequence

  5. XR_003950465.2 RNA Sequence