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Trim59 tripartite motif-containing 59 [ Mus musculus (house mouse) ]

Gene ID: 66949, updated on 23-Jun-2021

Summary

Official Symbol
Trim59provided by MGI
Official Full Name
tripartite motif-containing 59provided by MGI
Primary source
MGI:MGI:1914199
See related
Ensembl:ENSMUSG00000034317
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Mrf; Mrf1; TSBF; TSBF1; 2310035M22Rik; 2700022F13Rik
Expression
Biased expression in liver E14 (RPKM 15.4), liver E14.5 (RPKM 12.1) and 12 other tissues See more
Orthologs
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Genomic context

See Trim59 in Genome Data Viewer
Location:
3; 3 E1
Exon count:
4
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (68942625..68952075, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (69035292..69044742, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (68839216..68848664, complement)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene structural maintenance of chromosomes 4 Neighboring gene microRNA 16-2 Neighboring gene microRNA 15b Neighboring gene RIKEN cDNA 9630025H16 gene Neighboring gene karyopherin (importin) alpha 4 Neighboring gene predicted gene, 22009

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables ubiquitin protein ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables ubiquitin protein ligase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
PubMed 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
NOT part_of intraciliary transport particle B IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
tripartite motif-containing protein 59
Names
RING finger 1
RING finger protein 1
tumor suppressor TSBF1 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025863.3NP_080139.3  tripartite motif-containing protein 59

    See identical proteins and their annotated locations for NP_080139.3

    Status: VALIDATED

    Source sequence(s)
    AK009637, AK012269, AK016642, BE847098, CD541510
    Consensus CDS
    CCDS17402.1
    UniProtKB/Swiss-Prot
    Q922Y2
    Related
    ENSMUSP00000103432.2, ENSMUST00000107802.8
    Conserved Domains (2) summary
    cd16763
    Location:560
    RING-HC_TRIM59_C-V; RING finger, HC subclass, found in tripartite motif-containing protein 59 (TRIM59) and similar proteins
    cd19790
    Location:95134
    Bbox2_TRIM59_C-XI; B-box-type 2 zinc finger found in tripartite motif-containing protein 59 (TRIM59) and similar proteins

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    68942625..68952075 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006501917.4XP_006501980.1  tripartite motif-containing protein 59 isoform X1

    See identical proteins and their annotated locations for XP_006501980.1

    UniProtKB/Swiss-Prot
    Q922Y2
    Related
    ENSMUSP00000120270.2, ENSMUST00000136512.3
    Conserved Domains (2) summary
    cd16763
    Location:560
    RING-HC_TRIM59_C-V; RING finger, HC subclass, found in tripartite motif-containing protein 59 (TRIM59) and similar proteins
    cd19790
    Location:95134
    Bbox2_TRIM59_C-XI; B-box-type 2 zinc finger found in tripartite motif-containing protein 59 (TRIM59) and similar proteins
  2. XM_011240200.2XP_011238502.1  tripartite motif-containing protein 59 isoform X1

    See identical proteins and their annotated locations for XP_011238502.1

    UniProtKB/Swiss-Prot
    Q922Y2
    Conserved Domains (2) summary
    cd16763
    Location:560
    RING-HC_TRIM59_C-V; RING finger, HC subclass, found in tripartite motif-containing protein 59 (TRIM59) and similar proteins
    cd19790
    Location:95134
    Bbox2_TRIM59_C-XI; B-box-type 2 zinc finger found in tripartite motif-containing protein 59 (TRIM59) and similar proteins
  3. XM_011240201.4XP_011238503.1  tripartite motif-containing protein 59 isoform X1

    See identical proteins and their annotated locations for XP_011238503.1

    UniProtKB/Swiss-Prot
    Q922Y2
    Conserved Domains (2) summary
    cd16763
    Location:560
    RING-HC_TRIM59_C-V; RING finger, HC subclass, found in tripartite motif-containing protein 59 (TRIM59) and similar proteins
    cd19790
    Location:95134
    Bbox2_TRIM59_C-XI; B-box-type 2 zinc finger found in tripartite motif-containing protein 59 (TRIM59) and similar proteins
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