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Mtap methylthioadenosine phosphorylase [ Mus musculus (house mouse) ]

Gene ID: 66902, updated on 8-Dec-2018

Summary

Official Symbol
Mtapprovided by MGI
Official Full Name
methylthioadenosine phosphorylaseprovided by MGI
Primary source
MGI:MGI:1914152
See related
Ensembl:ENSMUSG00000062937
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
MSAP; 1300019I21Rik
Expression
Ubiquitous expression in CNS E11.5 (RPKM 13.2), bladder adult (RPKM 13.1) and 25 other tissues See more
Orthologs

Genomic context

See Mtap in Genome Data Viewer
Location:
4; 4 C4
Exon count:
8
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 4 NC_000070.6 (89137370..89181090)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (88783274..88826994)

Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene WNT induced non-coding RNA 1 Neighboring gene predicted gene 12602 Neighboring gene ribosomal protein L17 pseudogene Neighboring gene TGFB-induced factor homeobox 2, pseudogene 1 Neighboring gene cyclin dependent kinase inhibitor 2A

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
S-methyl-5-thioadenosine phosphorylase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
catalytic activity IEA
Inferred from Electronic Annotation
more info
 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
transferase activity, transferring glycosyl groups IEA
Inferred from Electronic Annotation
more info
 
transferase activity, transferring pentosyl groups IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
L-methionine salvage from methylthioadenosine IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
methylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
nucleoside metabolic process IEA
Inferred from Electronic Annotation
more info
 
purine ribonucleoside salvage IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytosol ISO
Inferred from Sequence Orthology
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
S-methyl-5'-thioadenosine phosphorylase
Names
5'-methylthioadenosine phosphorylase
MTA phosphorylase
MTAP
MTAPase
NP_077753.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_024433.2NP_077753.1  S-methyl-5'-thioadenosine phosphorylase

    See identical proteins and their annotated locations for NP_077753.1

    Status: VALIDATED

    Source sequence(s)
    AK005064, AK167319
    Consensus CDS
    CCDS18349.1
    UniProtKB/Swiss-Prot
    Q9CQ65
    Related
    ENSMUSP00000061092.7, ENSMUST00000058030.9
    Conserved Domains (1) summary
    cl00303
    Location:10273
    PNP_UDP_1; Phosphorylase superfamily

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000070.6 Reference GRCm38.p4 C57BL/6J

    Range
    89137370..89181090
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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