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Thap2 THAP domain containing, apoptosis associated protein 2 [ Mus musculus (house mouse) ]

Gene ID: 66816, updated on 5-Mar-2024

Summary

Official Symbol
Thap2provided by MGI
Official Full Name
THAP domain containing, apoptosis associated protein 2provided by MGI
Primary source
MGI:MGI:1914066
See related
Ensembl:ENSMUSG00000020137 AllianceGenome:MGI:1914066
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2900040O07Rik; 9030625G08Rik
Summary
Predicted to enable DNA binding activity and metal ion binding activity. Predicted to be located in nucleolus. Predicted to be active in nucleus. Orthologous to human THAP2 (THAP domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in whole brain E14.5 (RPKM 5.3), CNS E11.5 (RPKM 4.9) and 28 other tissues See more
Orthologs
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Genomic context

See Thap2 in Genome Data Viewer
Location:
10 D2; 10 63.51 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (115204303..115220340, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (115368398..115384435, complement)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 53632 Neighboring gene STARR-seq mESC enhancer starr_27937 Neighboring gene STARR-seq mESC enhancer starr_27939 Neighboring gene STARR-seq mESC enhancer starr_27942 Neighboring gene transmembrane protein 19 Neighboring gene soc-2 (suppressor of clear) homolog pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E1128 Neighboring gene predicted gene, 53633 Neighboring gene zinc finger, C3H1-type containing Neighboring gene STARR-positive B cell enhancer mm9_chr10:114916114-114916415 Neighboring gene leucine rich repeat containing G protein coupled receptor 5 Neighboring gene STARR-seq mESC enhancer starr_27944 Neighboring gene RIKEN cDNA A930009A15 gene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
THAP domain-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025780.4NP_080056.1  THAP domain-containing protein 2

    See identical proteins and their annotated locations for NP_080056.1

    Status: VALIDATED

    Source sequence(s)
    AK051198, AK081303, BG073155, BU698918, CX208940
    Consensus CDS
    CCDS24179.1
    UniProtKB/Swiss-Prot
    Q9D305
    Related
    ENSMUSP00000151353.2, ENSMUST00000218842.2
    Conserved Domains (1) summary
    pfam05485
    Location:482
    THAP; THAP domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    115204303..115220340 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)