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Tspan1 tetraspanin 1 [ Mus musculus (house mouse) ]

Gene ID: 66805, updated on 18-Apr-2024

Summary

Official Symbol
Tspan1provided by MGI
Official Full Name
tetraspanin 1provided by MGI
Primary source
MGI:MGI:1914055
See related
Ensembl:ENSMUSG00000028699 AllianceGenome:MGI:1914055
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
9030418M05Rik
Summary
Predicted to be involved in protein stabilization. Predicted to be located in several cellular components, including nucleoplasm; perinuclear region of cytoplasm; and vesicle. Predicted to be integral component of plasma membrane. Is expressed in central nervous system; gut; and retina nuclear layer. Orthologous to human TSPAN1 (tetraspanin 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in colon adult (RPKM 187.7), large intestine adult (RPKM 55.8) and 3 other tissues See more
Orthologs
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Genomic context

Location:
4 D1; 4 53.1 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (116019078..116024818, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (116161881..116167621, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 2510003B16 gene Neighboring gene STARR-seq mESC enhancer starr_11132 Neighboring gene leucine rich adaptor protein 1 Neighboring gene protein O-linked mannose beta 1,2-N-acetylglucosaminyltransferase Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:115849369-115849478 Neighboring gene Pik3r3 upstream reading frame Neighboring gene LLP homolog, pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Gene trapped (1) 
  • Targeted (1) 

General gene information

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in protein stabilization ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cell junction ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
located_in lysosome IEA
Inferred from Electronic Annotation
more info
 
located_in membrane ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in perinuclear region of cytoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in vesicle ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
tetraspanin-1
Names
tetraspan 1
tspan-1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_133681.4NP_598442.1  tetraspanin-1

    See identical proteins and their annotated locations for NP_598442.1

    Status: PROVISIONAL

    Source sequence(s)
    AL611947, AL670603
    Consensus CDS
    CCDS18508.1
    UniProtKB/Swiss-Prot
    A6PW93, Q99J59
    UniProtKB/TrEMBL
    A0A0A0MQL3
    Related
    ENSMUSP00000030465.4, ENSMUST00000030465.10
    Conserved Domains (1) summary
    pfam00335
    Location:7235
    Tetraspannin; Tetraspanin family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    116019078..116024818 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006503290.2XP_006503353.1  tetraspanin-1 isoform X1

    See identical proteins and their annotated locations for XP_006503353.1

    UniProtKB/Swiss-Prot
    A6PW93, Q99J59
    UniProtKB/TrEMBL
    A0A0A0MQL3
    Related
    ENSMUSP00000121906.2, ENSMUST00000143426.2
    Conserved Domains (1) summary
    pfam00335
    Location:7235
    Tetraspannin; Tetraspanin family