U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Prkrip1 Prkr interacting protein 1 (IL11 inducible) [ Mus musculus (house mouse) ]

Gene ID: 66801, updated on 13-Oct-2022

Summary

Official Symbol
Prkrip1provided by MGI
Official Full Name
Prkr interacting protein 1 (IL11 inducible)provided by MGI
Primary source
MGI:MGI:1914051
See related
Ensembl:ENSMUSG00000039737 AllianceGenome:MGI:1914051
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
C114; 8430424D23Rik
Summary
Enables double-stranded RNA binding activity; protein kinase binding activity; and protein kinase inhibitor activity. Acts upstream of or within negative regulation of protein kinase activity. Located in nucleolus. Orthologous to human PRKRIP1 (PRKR interacting protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 10.0), CNS E14 (RPKM 7.3) and 28 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Prkrip1 in Genome Data Viewer
Location:
5; 5 G2
Exon count:
6
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (136209211..136227808, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (136180357..136198954, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene alkB homolog 4, lysine demethylase Neighboring gene ORAI calcium release-activated calcium modulator 2 Neighboring gene ribosomal protein L7A pseudogene Neighboring gene SH2B adaptor protein 2 Neighboring gene predicted gene, 30408

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables double-stranded RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables double-stranded RNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein kinase binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein kinase binding IDA
Inferred from Direct Assay
more info
PubMed 
enables protein kinase inhibitor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein kinase inhibitor activity IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleolus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
part_of spliceosomal complex IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025774.3NP_080050.1  PRKR-interacting protein 1

    See identical proteins and their annotated locations for NP_080050.1

    Status: VALIDATED

    Source sequence(s)
    AK010961, AK020280
    Consensus CDS
    CCDS19754.1
    UniProtKB/Swiss-Prot
    Q9CWV6, Q9CY32
    UniProtKB/TrEMBL
    A0A8C6H018
    Related
    ENSMUSP00000120659.2, ENSMUST00000151786.8
    Conserved Domains (1) summary
    pfam06658
    Location:42125
    DUF1168; Protein of unknown function (DUF1168)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    136209211..136227808 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)