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Gid4 GID complex subunit 4, VID24 homolog [ Mus musculus (house mouse) ]

Gene ID: 66771, updated on 5-Mar-2024

Summary

Official Symbol
Gid4provided by MGI
Official Full Name
GID complex subunit 4, VID24 homologprovided by MGI
Primary source
MGI:MGI:1914021
See related
Ensembl:ENSMUSG00000018415 AllianceGenome:MGI:1914021
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4933439F18Rik
Summary
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of ubiquitin ligase complex. Orthologous to human GID4 (GID complex subunit 4 homolog). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in adrenal adult (RPKM 23.5), testis adult (RPKM 17.5) and 28 other tissues See more
Orthologs
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Genomic context

Location:
11 B2; 11 37.81 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (60307971..60336103)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (60417145..60445277)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene target of myb1-like 2 (chicken) Neighboring gene STARR-positive B cell enhancer ABC_E77 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene STARR-seq mESC enhancer starr_29650 Neighboring gene dynein regulatory complex subunit 3 Neighboring gene STARR-positive B cell enhancer ABC_E1139 Neighboring gene ATP synthase mitochondrial F1 complex assembly factor 2 Neighboring gene STARR-seq mESC enhancer starr_29653 Neighboring gene STARR-seq mESC enhancer starr_29654 Neighboring gene predicted gene 12268 Neighboring gene ribosomal protein S4, X-linked pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 
  • Endonuclease-mediated (4) 

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ubiquitin protein ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of ubiquitin ligase complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
glucose-induced degradation protein 4 homolog
Names
vacuolar import and degradation protein 24 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025757.4NP_080033.3  glucose-induced degradation protein 4 homolog

    See identical proteins and their annotated locations for NP_080033.3

    Status: VALIDATED

    Source sequence(s)
    BC046821, BY716798
    Consensus CDS
    CCDS24790.1
    UniProtKB/Swiss-Prot
    Q3TP79, Q7TT31, Q99JE9, Q9CPY6
    Related
    ENSMUSP00000064926.7, ENSMUST00000070681.7
    Conserved Domains (1) summary
    pfam09783
    Location:38206
    Vac_ImportDeg; Vacuolar import and degradation protein

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    60307971..60336103
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)