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Zfp600 zinc finger protein 600 [ Mus musculus (house mouse) ]

Gene ID: 667666, updated on 8-Dec-2022

Summary

Official Symbol
Zfp600provided by MGI
Official Full Name
zinc finger protein 600provided by MGI
Primary source
MGI:MGI:3705222
See related
Ensembl:ENSMUSG00000066007 AllianceGenome:MGI:3705222
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm13164
Summary
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in epiblast; primitive endoderm; and trophectoderm. Orthologous to human ZNF267 (zinc finger protein 267) and ZNF600 (zinc finger protein 600). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
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Genomic context

See Zfp600 in Genome Data Viewer
Location:
4 E1; 4
Exon count:
6
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (146093397..146135326)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (146156827..146198756)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene predicted gene 13035 Neighboring gene zinc finger protein 987 Neighboring gene vomeronasal 2, receptor, pseudogene 17 Neighboring gene predicted gene 13165 Neighboring gene high mobility group box 2 pseudogene Neighboring gene predicted gene 13167 Neighboring gene protein phosphatase 2, regulatory subunit B', alpha pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001177545.2NP_001171016.1  zinc finger protein 600

    See identical proteins and their annotated locations for NP_001171016.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AL606987, BC108352, CD541204, CD542866
    Consensus CDS
    CCDS51373.1
    UniProtKB/TrEMBL
    A2A7V0, E9PW48, Q32P07
    Related
    ENSMUSP00000090425.6, ENSMUST00000092750.12
    Conserved Domains (5) summary
    smart00349
    Location:2870
    KRAB; krueppel associated box
    COG5048
    Location:333730
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:281301
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:2867
    KRAB; KRAB box
    pfam13465
    Location:321346
    zf-H2C2_2; Zinc-finger double domain
  2. NM_001177546.2NP_001171017.1  zinc finger protein 600

    See identical proteins and their annotated locations for NP_001171017.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AL606987
    Consensus CDS
    CCDS51373.1
    UniProtKB/TrEMBL
    A2A7V0, E9PW48
    Related
    ENSMUSP00000126879.3, ENSMUST00000168483.9
    Conserved Domains (5) summary
    smart00349
    Location:2870
    KRAB; krueppel associated box
    COG5048
    Location:333730
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:281301
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:2867
    KRAB; KRAB box
    pfam13465
    Location:321346
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    146093397..146135326
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)