Format

Send to:

Choose Destination

Tab3 TGF-beta activated kinase 1/MAP3K7 binding protein 3 [ Mus musculus (house mouse) ]

Gene ID: 66724, updated on 31-Jan-2019

Summary

Official Symbol
Tab3provided by MGI
Official Full Name
TGF-beta activated kinase 1/MAP3K7 binding protein 3provided by MGI
Primary source
MGI:MGI:1913974
See related
Ensembl:ENSMUSG00000035476
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Map3k7ip3; mKIAA4135; 4921526G09Rik
Expression
Ubiquitous expression in liver E14 (RPKM 4.3), placenta adult (RPKM 4.2) and 27 other tissues See more
Orthologs

Genomic context

See Tab3 in Genome Data Viewer
Location:
X; X C1
Exon count:
11
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) X NC_000086.7 (85573851..85634469)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) X NC_000086.6 (82819361..82879808)

Chromosome X - NC_000086.7Genomic Context describing neighboring genes Neighboring gene predicted gene 16463 Neighboring gene ferritin, heavy polypeptide-like 17, member A Neighboring gene predicted gene, 39523 Neighboring gene RIKEN cDNA 5430427O19 gene Neighboring gene replication protein A 14 kDa subunit pseudogene Neighboring gene glycerol kinase

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • KIAA4135

Gene Ontology Provided by MGI

Function Evidence Code Pubs
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
positive regulation of I-kappaB kinase/NF-kappaB signaling ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
TGF-beta-activated kinase 1 and MAP3K7-binding protein 3
Names
TAK1-binding protein 3
TGF-beta-activated kinase 1-binding protein 3
mitogen-activated protein kinase kinase kinase 7-interacting protein 3

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001358447.1NP_001345376.1  TGF-beta-activated kinase 1 and MAP3K7-binding protein 3

    Status: VALIDATED

    Source sequence(s)
    AL645567, AL645586, BC090666
    Conserved Domains (3) summary
    smart00547
    Location:691713
    ZnF_RBZ; Zinc finger domain
    cd14362
    Location:950
    CUE_TAB2_TAB3; CUE domain found in the N-terminal of TGF-beta-activated kinase 1 and MAP3K7-binding proteins TAB2, TAB3 and similar proteins
    sd00029
    Location:691710
    zf-RanBP2; RanBP2-type Zn finger [structural motif]
  2. NM_025729.4NP_080005.2  TGF-beta-activated kinase 1 and MAP3K7-binding protein 3

    See identical proteins and their annotated locations for NP_080005.2

    Status: VALIDATED

    Source sequence(s)
    AK048222, AK220185, BC090666
    Consensus CDS
    CCDS41049.1
    UniProtKB/Swiss-Prot
    Q571K4
    UniProtKB/TrEMBL
    B1ASY9, Q9D5S8
    Related
    ENSMUSP00000039668.3, ENSMUST00000048250.9
    Conserved Domains (3) summary
    smart00547
    Location:691713
    ZnF_RBZ; Zinc finger domain
    cd14362
    Location:950
    CUE_TAB2_TAB3; CUE domain found in the N-terminal of TGF-beta-activated kinase 1 and MAP3K7-binding proteins TAB2, TAB3 and similar proteins
    sd00029
    Location:691710
    zf-RanBP2; RanBP2-type Zn finger [structural motif]

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000086.7 Reference GRCm38.p4 C57BL/6J

    Range
    85573851..85634469
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017318604.1XP_017174093.1  TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 isoform X1

    UniProtKB/Swiss-Prot
    Q571K4
    UniProtKB/TrEMBL
    B1ASY9
    Conserved Domains (3) summary
    smart00547
    Location:691713
    ZnF_RBZ; Zinc finger domain
    cd14362
    Location:950
    CUE_TAB2_TAB3; CUE domain found in the N-terminal of TGF-beta-activated kinase 1 and MAP3K7-binding proteins TAB2, TAB3 and similar proteins
    sd00029
    Location:691710
    zf-RanBP2; RanBP2-type Zn finger [structural motif]
  2. XM_006528238.3XP_006528301.1  TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 isoform X1

    See identical proteins and their annotated locations for XP_006528301.1

    UniProtKB/Swiss-Prot
    Q571K4
    UniProtKB/TrEMBL
    B1ASY9
    Conserved Domains (3) summary
    smart00547
    Location:691713
    ZnF_RBZ; Zinc finger domain
    cd14362
    Location:950
    CUE_TAB2_TAB3; CUE domain found in the N-terminal of TGF-beta-activated kinase 1 and MAP3K7-binding proteins TAB2, TAB3 and similar proteins
    sd00029
    Location:691710
    zf-RanBP2; RanBP2-type Zn finger [structural motif]
  3. XM_006528239.2XP_006528302.1  TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 isoform X1

    See identical proteins and their annotated locations for XP_006528302.1

    UniProtKB/Swiss-Prot
    Q571K4
    UniProtKB/TrEMBL
    B1ASY9
    Conserved Domains (3) summary
    smart00547
    Location:691713
    ZnF_RBZ; Zinc finger domain
    cd14362
    Location:950
    CUE_TAB2_TAB3; CUE domain found in the N-terminal of TGF-beta-activated kinase 1 and MAP3K7-binding proteins TAB2, TAB3 and similar proteins
    sd00029
    Location:691710
    zf-RanBP2; RanBP2-type Zn finger [structural motif]
  4. XM_017318605.1XP_017174094.1  TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 isoform X2

    Conserved Domains (2) summary
    cd14362
    Location:950
    CUE_TAB2_TAB3; CUE domain found in the N-terminal of TGF-beta-activated kinase 1 and MAP3K7-binding proteins TAB2, TAB3 and similar proteins
    pfam03153
    Location:122291
    TFIIA; Transcription factor IIA, alpha/beta subunit
Support Center