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Zscan25 zinc finger and SCAN domain containing 25 [ Mus musculus (house mouse) ]

Gene ID: 666311, updated on 5-Mar-2024

Summary

Official Symbol
Zscan25provided by MGI
Official Full Name
zinc finger and SCAN domain containing 25provided by MGI
Primary source
MGI:MGI:3647079
See related
Ensembl:ENSMUSG00000070420 AllianceGenome:MGI:3647079
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Zfp498; EG666311
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Orthologous to human ZSCAN25 (zinc finger and SCAN domain containing 25). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in ovary adult (RPKM 9.9), thymus adult (RPKM 8.9) and 28 other tissues See more
Orthologs
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Genomic context

See Zscan25 in Genome Data Viewer
Location:
5 G2; 5 85.17 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (145217261..145229050)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (145280451..145292240)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E4805 Neighboring gene zinc finger protein 655 Neighboring gene predicted gene 9710 Neighboring gene STARR-positive B cell enhancer ABC_E6398 Neighboring gene STARR-seq mESC enhancer starr_14828 Neighboring gene STARR-seq mESC enhancer starr_14829 Neighboring gene STARR-seq mESC enhancer starr_14831 Neighboring gene cytochrome P450, family 3, subfamily a, polypeptide 57 Neighboring gene sperm motility kinase 3A pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

General protein information

Preferred Names
zinc finger and SCAN domain-containing protein 25
Names
zinc finger protein 498

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081431.2NP_001074900.1  zinc finger and SCAN domain-containing protein 25 isoform 1

    See identical proteins and their annotated locations for NP_001074900.1

    Status: VALIDATED

    Source sequence(s)
    AC127411
    Consensus CDS
    CCDS39387.1
    UniProtKB/TrEMBL
    B2RX31
    Related
    ENSMUSP00000091664.4, ENSMUST00000094116.5
    Conserved Domains (4) summary
    COG5048
    Location:338531
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:404424
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam02023
    Location:38120
    SCAN; SCAN domain
    cl02581
    Location:230258
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
  2. NM_001384204.1NP_001371133.1  zinc finger and SCAN domain-containing protein 25 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC127411
    Conserved Domains (4) summary
    COG5048
    Location:272465
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:338358
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam02023
    Location:38120
    SCAN; SCAN domain
    cl02581
    Location:164192
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
  3. NM_001384205.1NP_001371134.1  zinc finger and SCAN domain-containing protein 25 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC127411
    Conserved Domains (4) summary
    COG5048
    Location:123288
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:189209
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:284309
    zf-H2C2_2; Zinc-finger double domain
    cl02581
    Location:1543
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
  4. NM_001384206.1NP_001371135.1  zinc finger and SCAN domain-containing protein 25 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC127411
    UniProtKB/TrEMBL
    B2RX31
    Conserved Domains (4) summary
    COG5048
    Location:338531
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:404424
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam02023
    Location:38120
    SCAN; SCAN domain
    cl02581
    Location:230258
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
  5. NM_001384207.1NP_001371136.1  zinc finger and SCAN domain-containing protein 25 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC127411
    Conserved Domains (4) summary
    COG5048
    Location:123288
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:189209
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:284309
    zf-H2C2_2; Zinc-finger double domain
    cl02581
    Location:1543
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    145217261..145229050
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)