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Gdpd1 glycerophosphodiester phosphodiesterase domain containing 1 [ Mus musculus (house mouse) ]

Gene ID: 66569, updated on 26-Sep-2022

Summary

Official Symbol
Gdpd1provided by MGI
Official Full Name
glycerophosphodiester phosphodiesterase domain containing 1provided by MGI
Primary source
MGI:MGI:1913819
See related
Ensembl:ENSMUSG00000061666 AllianceGenome:MGI:1913819
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2610020H15Rik
Summary
Enables lysophospholipase activity and phosphoric diester hydrolase activity. Acts upstream of or within N-acylethanolamine metabolic process and phospholipid metabolic process. Located in membrane and perinuclear region of cytoplasm. Is expressed in several structures, including adrenal medulla; alimentary system; nervous system; sensory organ; and urinary system. Orthologous to human GDPD1 (glycerophosphodiester phosphodiesterase domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in large intestine adult (RPKM 61.4), testis adult (RPKM 41.0) and 15 other tissues See more
Orthologs
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Genomic context

See Gdpd1 in Genome Data Viewer
Location:
11; 11 C
Exon count:
10
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (86924620..86964963, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (87033794..87074137, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene yippee like 2 Neighboring gene predicted gene, 51915 Neighboring gene predicted gene, 22387 Neighboring gene SMG8 nonsense mediated mRNA decay factor Neighboring gene proline rich 11

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables lysophospholipase activity EXP
Inferred from Experiment
more info
PubMed 
enables lysophospholipase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables lysophospholipase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables lysophospholipase activity ISO
Inferred from Sequence Orthology
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables phosphoric diester hydrolase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables phosphoric diester hydrolase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables phosphoric diester hydrolase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables phosphoric diester hydrolase activity ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in endoplasmic reticulum membrane TAS
Traceable Author Statement
more info
 
located_in membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in perinuclear region of cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
lysophospholipase D GDPD1
Names
glycerophosphodiester phosphodiesterase 4
glycerophosphodiester phosphodiesterase domain-containing protein 1
NP_079914.1
XP_036012792.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025638.2NP_079914.1  lysophospholipase D GDPD1

    See identical proteins and their annotated locations for NP_079914.1

    Status: VALIDATED

    Source sequence(s)
    AK013864, AK039183, BY282485, BY697784, CA451251
    Consensus CDS
    CCDS25206.1
    UniProtKB/Swiss-Prot
    Q9CRY7, Q9D4X7
    UniProtKB/TrEMBL
    A0A6P5QPV8, A0A8C6MTG1
    Related
    ENSMUSP00000020804.8, ENSMUST00000020804.8
    Conserved Domains (1) summary
    cd08612
    Location:14311
    GDPD_GDE4; Glycerophosphodiester phosphodiesterase domain of mammalian glycerophosphodiester phosphodiesterase GDE4 and similar proteins

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    86924620..86964963 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036156899.1XP_036012792.1  lysophospholipase D GDPD1 isoform X1

    Conserved Domains (1) summary
    cd08612
    Location:1242
    GDPD_GDE4; Glycerophosphodiester phosphodiesterase domain of mammalian glycerophosphodiester phosphodiesterase GDE4 and similar proteins