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Atp5mk ATP synthase membrane subunit k [ Mus musculus (house mouse) ]

Gene ID: 66477, updated on 5-Mar-2024

Summary

Official Symbol
Atp5mkprovided by MGI
Official Full Name
ATP synthase membrane subunit kprovided by MGI
Primary source
MGI:MGI:1891435
See related
Ensembl:ENSMUSG00000071528 AllianceGenome:MGI:1891435
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Usmg5; Atp5md; 2010301L15Rik
Summary
Located in mitochondrion. Is expressed in several structures, including brain; cardiovascular system; genitourinary system; gut; and immune system. Human ortholog(s) of this gene implicated in mitochondrial complex V (ATP synthase) deficiency nuclear type 6. Orthologous to human ATP5MK (ATP synthase membrane subunit k). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in placenta adult (RPKM 151.0), CNS E18 (RPKM 144.4) and 22 other tissues See more
Orthologs
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Genomic context

Location:
19 C3; 19 39.23 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (47071910..47079086, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (47083471..47090647, complement)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene polycomb group ring finger 6 Neighboring gene STARR-positive B cell enhancer ABC_E11037 Neighboring gene STARR-seq mESC enhancer starr_46338 Neighboring gene predicted gene, 23140 Neighboring gene STARR-positive B cell enhancer ABC_E1979 Neighboring gene TATA-box binding protein associated factor 5 Neighboring gene STARR-positive B cell enhancer ABC_E11038 Neighboring gene programmed cell death 11 Neighboring gene STARR-positive B cell enhancer ABC_E11039 Neighboring gene STARR-positive B cell enhancer ABC_E8754 Neighboring gene STARR-seq mESC enhancer starr_46339 Neighboring gene calcium homeostasis modulator family member 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
ATP synthase membrane subunit K, mitochondrial
Names
ATP synthase membrane subunit DAPIT, mitochondrial
diabetes-associated protein in insulin-sensitive tissues
up-regulated during skeletal muscle growth protein 5
upregulated during skeletal muscle growth 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_023211.5NP_075700.2  ATP synthase membrane subunit K, mitochondrial

    See identical proteins and their annotated locations for NP_075700.2

    Status: VALIDATED

    Source sequence(s)
    AC124724
    Consensus CDS
    CCDS38014.1
    UniProtKB/Swiss-Prot
    Q78IK2, Q9ER48
    Related
    ENSMUSP00000093713.4, ENSMUST00000096014.5
    Conserved Domains (1) summary
    pfam14960
    Location:151
    ATP_synth_reg; ATP synthase regulation

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    47071910..47079086 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)