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Cnpy4 canopy FGF signaling regulator 4 [ Mus musculus (house mouse) ]

Gene ID: 66455, updated on 12-May-2024


Official Symbol
Cnpy4provided by MGI
Official Full Name
canopy FGF signaling regulator 4provided by MGI
Primary source
See related
Ensembl:ENSMUSG00000036968 AllianceGenome:MGI:1913705
Gene type
protein coding
RefSeq status
Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Enables signaling receptor binding activity. Predicted to be involved in positive regulation of protein localization to plasma membrane. Predicted to act upstream of or within regulation of protein localization. Predicted to be located in extracellular region. Orthologous to human CNPY4 (canopy FGF signaling regulator 4). [provided by Alliance of Genome Resources, Apr 2022]
Broad expression in CNS E11.5 (RPKM 23.1), limb E14.5 (RPKM 12.8) and 19 other tissues See more
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Genomic context

See Cnpy4 in Genome Data Viewer
5 G2; 5 76.98 cM
Exon count:
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (138185768..138192180)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (138187535..138193894)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene microRNA 106b Neighboring gene minichromosome maintenance complex component 7 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:138612151-138612338 Neighboring gene STARR-positive B cell enhancer ABC_E1693 Neighboring gene STARR-positive B cell enhancer ABC_E1694 Neighboring gene adaptor-related protein complex AP-4, mu 1 Neighboring gene TATA-box binding protein associated factor 6 Neighboring gene STARR-seq mESC enhancer starr_14665 Neighboring gene metallo-beta-lactamase domain containing 1 Neighboring gene predicted gene 454

Genomic regions, transcripts, and products


  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a



Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Targeted (3)  1 citation
  • Transgenic (1) 


Products Interactant Other Gene Complex Source Pubs Description

General gene information


Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables signaling receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
enables signaling receptor binding IPI
Inferred from Physical Interaction
more info
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
located_in extracellular region IEA
Inferred from Electronic Annotation
more info

General protein information

Preferred Names
protein canopy homolog 4
canopy 4 homolog
protein associated with Tlr4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001419173.1NP_001406102.1  protein canopy homolog 4 isoform 1 precursor

    Status: VALIDATED

    Source sequence(s)
    AC151719, AC159257
  2. NM_001419174.1NP_001406103.1  protein canopy homolog 4 isoform 3 precursor

    Status: VALIDATED

    Source sequence(s)
    AC151719, AC159257
  3. NM_178612.5NP_848727.1  protein canopy homolog 4 isoform 2 precursor

    See identical proteins and their annotated locations for NP_848727.1

    Status: VALIDATED

    Source sequence(s)
    AC151719, AC159257
    Consensus CDS
    Q8BQ47, Q8BT84, Q8BTB1, Q8CCG0
    ENSMUSP00000106559.3, ENSMUST00000110934.9
    Conserved Domains (1) summary
    DUF3456; TLR4 regulator and MIR-interacting MSAP

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J


  1. NC_000071.7 Reference GRCm39 C57BL/6J

    GenBank, FASTA, Sequence Viewer (Graphics)