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Uggt2 UDP-glucose glycoprotein glucosyltransferase 2 [ Mus musculus (house mouse) ]

Gene ID: 66435, updated on 31-Jan-2019

Summary

Official Symbol
Uggt2provided by MGI
Official Full Name
UDP-glucose glycoprotein glucosyltransferase 2provided by MGI
Primary source
MGI:MGI:1913685
See related
Ensembl:ENSMUSG00000042104
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ugcgl2; AW047562; 1810064L21Rik; 3110001A05Rik; 3110027P15Rik; A230065J02Rik
Expression
Broad expression in CNS E18 (RPKM 4.9), CNS E14 (RPKM 4.9) and 20 other tissues See more
Orthologs

Genomic context

See Uggt2 in Genome Data Viewer
Location:
14; 14 E4
Exon count:
46
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 14 NC_000080.6 (118981765..119099450, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (119384207..119498656, complement)

Chromosome 14 - NC_000080.6Genomic Context describing neighboring genes Neighboring gene coiled-coil domain-containing protein 58 pseudogene Neighboring gene DAZ interacting protein 1 Neighboring gene DnaJ heat shock protein family (Hsp40) member C3 Neighboring gene predicted gene, 16835 Neighboring gene heparan sulfate 6-O-sulfotransferase 3 Neighboring gene tera pseudogene Neighboring gene CD24a antigen pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

General gene information

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
UDP-glucose:glycoprotein glucosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
unfolded protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
ER-associated misfolded protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein N-linked glycosylation via asparagine IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein-containing complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
UDP-glucose:glycoprotein glucosyltransferase 2
Names
UDP-glucose ceramide glucosyltransferase-like 2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081252.2NP_001074721.2  UDP-glucose:glycoprotein glucosyltransferase 2 precursor

    See identical proteins and their annotated locations for NP_001074721.2

    Status: VALIDATED

    Source sequence(s)
    AC154760
    Consensus CDS
    CCDS37013.2
    UniProtKB/TrEMBL
    E9Q4X2
    Related
    ENSMUSP00000121249.1, ENSMUST00000156203.7
    Conserved Domains (2) summary
    cd06432
    Location:12191466
    GT8_HUGT1_C_like; The C-terminal domain of HUGT1-like is highly homologous to the GT 8 family
    pfam06427
    Location:241181
    UDP-g_GGTase; UDP-glucose:Glycoprotein Glucosyltransferase

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000080.6 Reference GRCm38.p4 C57BL/6J

    Range
    118981765..119099450 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017316123.1XP_017171612.1  UDP-glucose:glycoprotein glucosyltransferase 2 isoform X4

    Conserved Domains (2) summary
    cd06432
    Location:10021249
    GT8_HUGT1_C_like; The C-terminal domain of HUGT1-like is highly homologous to the GT 8 family
    pfam06427
    Location:1964
    UDP-g_GGTase; UDP-glucose:Glycoprotein Glucosyltransferase
  2. XM_017316124.1XP_017171613.1  UDP-glucose:glycoprotein glucosyltransferase 2 isoform X6

  3. XM_017316125.1XP_017171614.1  UDP-glucose:glycoprotein glucosyltransferase 2 isoform X7

    Conserved Domains (2) summary
    cd06432
    Location:8431090
    GT8_HUGT1_C_like; The C-terminal domain of HUGT1-like is highly homologous to the GT 8 family
    pfam06427
    Location:11805
    UDP-g_GGTase; UDP-glucose:Glycoprotein Glucosyltransferase
  4. XM_017316122.1XP_017171611.1  UDP-glucose:glycoprotein glucosyltransferase 2 isoform X2

    Conserved Domains (2) summary
    cd06432
    Location:12191455
    GT8_HUGT1_C_like; The C-terminal domain of HUGT1-like is highly homologous to the GT 8 family
    pfam06427
    Location:241181
    UDP-g_GGTase; UDP-glucose:Glycoprotein Glucosyltransferase
  5. XM_017316121.1XP_017171610.1  UDP-glucose:glycoprotein glucosyltransferase 2 isoform X1

    Conserved Domains (2) summary
    cd06432
    Location:12191466
    GT8_HUGT1_C_like; The C-terminal domain of HUGT1-like is highly homologous to the GT 8 family
    pfam06427
    Location:241181
    UDP-g_GGTase; UDP-glucose:Glycoprotein Glucosyltransferase
  6. XM_006519376.2XP_006519439.1  UDP-glucose:glycoprotein glucosyltransferase 2 isoform X3

    Conserved Domains (2) summary
    pfam06427
    Location:241181
    UDP-g_GGTase; UDP-glucose:Glycoprotein Glucosyltransferase
    cl11394
    Location:12191417
    Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold
  7. XM_006519380.3XP_006519443.1  UDP-glucose:glycoprotein glucosyltransferase 2 isoform X5

    See identical proteins and their annotated locations for XP_006519443.1

    Conserved Domains (2) summary
    pfam06427
    Location:241181
    UDP-g_GGTase; UDP-glucose:Glycoprotein Glucosyltransferase
    cl11394
    Location:12191235
    Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold
  8. XM_006519382.1XP_006519445.1  UDP-glucose:glycoprotein glucosyltransferase 2 isoform X8

    Conserved Domains (1) summary
    pfam06427
    Location:241065
    UDP-g_GGTase; UDP-glucose:Glycoprotein Glucosyltransferase

RNA

  1. XR_001781137.1 RNA Sequence

  2. XR_001781138.1 RNA Sequence

  3. XR_001781139.1 RNA Sequence

  4. XR_001781140.1 RNA Sequence

  5. XR_001781141.1 RNA Sequence

  6. XR_001781143.1 RNA Sequence

  7. XR_001781142.1 RNA Sequence

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_025561.1: Suppressed sequence

    Description
    NM_025561.1: This RefSeq was suppressed temporarily based on the calculation that the annotated protein was shorter than a protein or proteins from a putative ortholog.
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