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Ndufb11b NADH:ubiquinone oxidoreductase subunit B11B [ Mus musculus (house mouse) ]

Gene ID: 66346, updated on 28-Oct-2024

Summary

Official Symbol
Ndufb11bprovided by MGI
Official Full Name
NADH:ubiquinone oxidoreductase subunit B11Bprovided by MGI
Primary source
MGI:MGI:1913596
See related
Ensembl:ENSMUSG00000061633 AllianceGenome:MGI:1913596
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1700029P11Rik
Summary
Predicted to be involved in mitochondrial respiratory chain complex I assembly. Located in mitochondrion. Is expressed in limb long bone; otic capsule; thoracic segment skeleton; and viscerocranium. Human ortholog(s) of this gene implicated in linear skin defects with multiple congenital anomalies 3 and nuclear type mitochondrial complex I deficiency 30. Orthologous to human NDUFB11 (NADH:ubiquinone oxidoreductase subunit B11). [provided by Alliance of Genome Resources, Oct 2024]
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Genomic context

See Ndufb11b in Genome Data Viewer
Location:
15 E1; 15 38.32 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (81864741..81865764)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (81980540..81981563)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_39278 Neighboring gene cytochrome P450, family 2, subfamily d, polypeptide 67, pseudogene Neighboring gene 40S ribosomal protein S14 Neighboring gene X-ray repair complementing defective repair in Chinese hamster cells 6 Neighboring gene desumoylating isopeptidase 1 Neighboring gene STARR-positive B cell enhancer ABC_E7400 Neighboring gene SNU13 homolog, small nuclear ribonucleoprotein (U4/U6.U5)

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in mitochondrial respiratory chain complex I assembly ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in mitochondrial inner membrane ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrion HDA PubMed 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 
part_of respiratory chain complex I IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of respiratory chain complex I ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial-like
NP_079779.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025503.4NP_079779.2  NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial-like

    See identical proteins and their annotated locations for NP_079779.2

    Status: VALIDATED

    Source sequence(s)
    AC102103, AV460581, BC048460
    Consensus CDS
    CCDS37152.1
    UniProtKB/TrEMBL
    Q9CQ68, Q9D9S8
    Related
    ENSMUSP00000074190.4, ENSMUST00000074608.4
    Conserved Domains (1) summary
    pfam10183
    Location:43130
    ESSS; ESSS subunit of NADH:ubiquinone oxidoreductase (complex I)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    81864741..81865764
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)