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Alg5 ALG5 dolichyl-phosphate beta-glucosyltransferase [ Mus musculus (house mouse) ]

Gene ID: 66248, updated on 5-Mar-2024

Summary

Official Symbol
Alg5provided by MGI
Official Full Name
ALG5 dolichyl-phosphate beta-glucosyltransferaseprovided by MGI
Primary source
MGI:MGI:1913498
See related
Ensembl:ENSMUSG00000036632 AllianceGenome:MGI:1913498
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1500026A19Rik; 2600005J22Rik
Summary
Predicted to enable dolichyl-phosphate beta-glucosyltransferase activity. Acts upstream of or within determination of left/right symmetry. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human ALG5 (ALG5 dolichyl-phosphate beta-glucosyltransferase). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in placenta adult (RPKM 25.9), bladder adult (RPKM 13.0) and 28 other tissues See more
Orthologs
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Genomic context

See Alg5 in Genome Data Viewer
Location:
3 C; 3 25.6 cM
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (54642960..54657216)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (54735539..54749795)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene REX1, RNA exonuclease 1 homolog pseudogene Neighboring gene STARR-seq mESC enhancer starr_07679 Neighboring gene STARR-positive B cell enhancer ABC_E8986 Neighboring gene STARR-seq mESC enhancer starr_07681 Neighboring gene SPT20 SAGA complex component Neighboring gene STARR-positive B cell enhancer ABC_E7912 Neighboring gene STARR-positive B cell enhancer ABC_E10181 Neighboring gene exosome component 8 Neighboring gene SMAD family member 9 Neighboring gene STARR-seq mESC enhancer starr_07686 Neighboring gene regulatory factor X-associated protein

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables dolichyl-phosphate beta-glucosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within determination of left/right symmetry IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein N-linked glycosylation IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
dolichyl-phosphate beta-glucosyltransferase
Names
Alg5 homolog
asparagine-linked glycosylation 5 (dolichyl-phosphate beta-glucosyltransferase)
asparagine-linked glycosylation 5 homolog (yeast, dolichyl-phosphate beta-glucosyltransferase)
asparagine-linked glycosylation protein 5 homolog
dolP-glucosyltransferase
NP_079718.1
XP_036019115.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025442.3NP_079718.1  dolichyl-phosphate beta-glucosyltransferase

    See identical proteins and their annotated locations for NP_079718.1

    Status: VALIDATED

    Source sequence(s)
    AC100927
    Consensus CDS
    CCDS17353.1
    UniProtKB/Swiss-Prot
    Q9DB25
    UniProtKB/TrEMBL
    Q9CTE8
    Related
    ENSMUSP00000035879.4, ENSMUST00000044567.4
    Conserved Domains (1) summary
    cd04188
    Location:69289
    DPG_synthase; DPG_synthase is involved in protein N-linked glycosylation

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    54642960..54657216
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036163222.1XP_036019115.1  dolichyl-phosphate beta-glucosyltransferase isoform X1

    UniProtKB/TrEMBL
    Q9CTE8
    Conserved Domains (1) summary
    cd04188
    Location:52272
    DPG_synthase; DPG_synthase is involved in protein N-linked glycosylation