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Tmem9 transmembrane protein 9 [ Mus musculus (house mouse) ]

Gene ID: 66241, updated on 26-Sep-2022

Summary

Official Symbol
Tmem9provided by MGI
Official Full Name
transmembrane protein 9provided by MGI
Primary source
MGI:MGI:1913491
See related
Ensembl:ENSMUSG00000026411 AllianceGenome:MGI:1913491
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1500015G18Rik
Summary
Involved in positive regulation of canonical Wnt signaling pathway and regulation of protein catabolic process. Predicted to be located in bounding membrane of organelle; intercellular bridge; and mitotic spindle. Is expressed in central nervous system; retina; and tooth. Orthologous to human TMEM9 (transmembrane protein 9). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in ovary adult (RPKM 68.3), kidney adult (RPKM 56.8) and 28 other tissues See more
Orthologs
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Genomic context

See Tmem9 in Genome Data Viewer
Location:
1; 1 E4
Exon count:
8
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (135935957..135962768)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (136008219..136035030)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene troponin T2, cardiac Neighboring gene plakophilin 1 Neighboring gene immunoglobulin-like and fibronectin type III domain containing 1 Neighboring gene calcium channel, voltage-dependent, L type, alpha 1S subunit Neighboring gene achaete-scute family bHLH transcription factor 5

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (3)  1 citation
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Component Evidence Code Pubs
located_in endosome IEA
Inferred from Electronic Annotation
more info
 
located_in intercellular bridge ISO
Inferred from Sequence Orthology
more info
 
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
located_in late endosome ISO
Inferred from Sequence Orthology
more info
PubMed 
located_in lysosomal membrane ISO
Inferred from Sequence Orthology
more info
 
located_in lysosome ISO
Inferred from Sequence Orthology
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in microtubule cytoskeleton ISO
Inferred from Sequence Orthology
more info
 
located_in mitotic spindle ISO
Inferred from Sequence Orthology
more info
 
located_in multivesicular body membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
proton-transporting V-type ATPase complex assembly regulator TMEM9
Names
v-ATPase assembly regulator TMEM9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001160145.1NP_001153617.1  proton-transporting V-type ATPase complex assembly regulator TMEM9 precursor

    See identical proteins and their annotated locations for NP_001153617.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. All three variants encode the same protein.
    Source sequence(s)
    AC108813, AC124375, BQ918002
    Consensus CDS
    CCDS15323.1
    UniProtKB/Swiss-Prot
    Q3U459, Q9CR23
    Related
    ENSMUSP00000128185.2, ENSMUST00000165125.8
    Conserved Domains (1) summary
    pfam05434
    Location:44182
    Tmemb_9; TMEM9
  2. NM_001160146.1NP_001153618.1  proton-transporting V-type ATPase complex assembly regulator TMEM9 precursor

    See identical proteins and their annotated locations for NP_001153618.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. All three variants encode the same protein.
    Source sequence(s)
    AC108813, AC124375, CX208138
    Consensus CDS
    CCDS15323.1
    UniProtKB/Swiss-Prot
    Q3U459, Q9CR23
    Related
    ENSMUSP00000113416.2, ENSMUST00000117950.2
    Conserved Domains (1) summary
    pfam05434
    Location:44182
    Tmemb_9; TMEM9
  3. NM_025439.3NP_079715.1  proton-transporting V-type ATPase complex assembly regulator TMEM9 precursor

    See identical proteins and their annotated locations for NP_079715.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. All three variants encode the same protein.
    Source sequence(s)
    AC108813, AC124375, CA460035
    Consensus CDS
    CCDS15323.1
    UniProtKB/Swiss-Prot
    Q3U459, Q9CR23
    Related
    ENSMUSP00000065409.9, ENSMUST00000063719.15
    Conserved Domains (1) summary
    pfam05434
    Location:44182
    Tmemb_9; TMEM9

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    135935957..135962768
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)