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Rgcc regulator of cell cycle [ Mus musculus (house mouse) ]

Gene ID: 66214, updated on 9-Apr-2019

Summary

Official Symbol
Rgccprovided by MGI
Official Full Name
regulator of cell cycleprovided by MGI
Primary source
MGI:MGI:1913464
See related
Ensembl:ENSMUSG00000022018
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Rgc32; Rgc-32; 1190002H23Rik
Expression
Biased expression in adrenal adult (RPKM 435.0), subcutaneous fat pad adult (RPKM 253.5) and 14 other tissues See more
Orthologs

Genomic context

See Rgcc in Genome Data Viewer
Location:
14; 14 D3
Exon count:
5
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 14 NC_000080.6 (79288750..79301635, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (79688557..79701442, complement)

Chromosome 14 - NC_000080.6Genomic Context describing neighboring genes Neighboring gene von Willebrand factor A domain containing 8 Neighboring gene predicted gene 4632 Neighboring gene zinc finger protein 957 Neighboring gene predicted gene, 46472 Neighboring gene N(alpha)-acetyltransferase 16, NatA auxiliary subunit

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
R-SMAD binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein kinase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein kinase activator activity ISO
Inferred from Sequence Orthology
more info
PubMed 
protein kinase binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein kinase binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
G1/S transition of mitotic cell cycle ISO
Inferred from Sequence Orthology
more info
PubMed 
cell cycle IEA
Inferred from Electronic Annotation
more info
 
cellular response to hypoxia ISO
Inferred from Sequence Orthology
more info
 
complement activation ISO
Inferred from Sequence Orthology
more info
 
fibroblast activation IMP
Inferred from Mutant Phenotype
more info
PubMed 
mitotic cell cycle arrest ISO
Inferred from Sequence Orthology
more info
 
negative regulation of angiogenesis ISO
Inferred from Sequence Orthology
more info
 
negative regulation of blood vessel endothelial cell migration ISO
Inferred from Sequence Orthology
more info
 
negative regulation of cell proliferation ISO
Inferred from Sequence Orthology
more info
 
negative regulation of cell-cell adhesion mediated by cadherin ISO
Inferred from Sequence Orthology
more info
 
negative regulation of cytokine secretion ISO
Inferred from Sequence Orthology
more info
 
negative regulation of endothelial cell proliferation ISO
Inferred from Sequence Orthology
more info
 
negative regulation of exit from mitosis ISO
Inferred from Sequence Orthology
more info
 
negative regulation of fibroblast growth factor production ISO
Inferred from Sequence Orthology
more info
 
negative regulation of mitotic cell cycle phase transition ISO
Inferred from Sequence Orthology
more info
 
positive regulation of DNA-binding transcription factor activity ISO
Inferred from Sequence Orthology
more info
 
positive regulation of G1/S transition of mitotic cell cycle ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cell cycle arrest ISO
Inferred from Sequence Orthology
more info
 
positive regulation of collagen biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cyclin-dependent protein serine/threonine kinase activity ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cytokine secretion ISO
Inferred from Sequence Orthology
more info
 
positive regulation of endothelial cell apoptotic process ISO
Inferred from Sequence Orthology
more info
 
positive regulation of epithelial to mesenchymal transition ISO
Inferred from Sequence Orthology
more info
 
positive regulation of extracellular matrix assembly ISO
Inferred from Sequence Orthology
more info
 
positive regulation of extracellular matrix constituent secretion ISO
Inferred from Sequence Orthology
more info
 
positive regulation of gene expression ISO
Inferred from Sequence Orthology
more info
 
positive regulation of mitotic nuclear division ISO
Inferred from Sequence Orthology
more info
 
positive regulation of stress fiber assembly ISO
Inferred from Sequence Orthology
more info
 
positive regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
regulation of cell cycle IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
centrosome ISO
Inferred from Sequence Orthology
more info
 
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm ISO
Inferred from Sequence Orthology
more info
PubMed 
cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
nucleolus ISO
Inferred from Sequence Orthology
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
PubMed 

General protein information

Preferred Names
regulator of cell cycle RGCC
Names
response gene to complement 32 protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025427.2NP_079703.2  regulator of cell cycle RGCC

    See identical proteins and their annotated locations for NP_079703.2

    Status: VALIDATED

    Source sequence(s)
    BC049580, BY083770, CK792184
    Consensus CDS
    CCDS49552.1
    UniProtKB/Swiss-Prot
    Q9DBX1
    Related
    ENSMUSP00000022595.7, ENSMUST00000022595.7
    Conserved Domains (1) summary
    pfam15151
    Location:27137
    RGCC; Response gene to complement 32 protein family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000080.6 Reference GRCm38.p4 C57BL/6J

    Range
    79288750..79301635 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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