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Virma vir like m6A methyltransferase associated [ Mus musculus (house mouse) ]

Gene ID: 66185, updated on 31-Jan-2019

Summary

Official Symbol
Virmaprovided by MGI
Official Full Name
vir like m6A methyltransferase associatedprovided by MGI
Primary source
MGI:MGI:1913435
See related
Ensembl:ENSMUSG00000040720
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Kiaa1429; mKIAA1429; 1110037F02Rik; 4930422M05Rik
Expression
Ubiquitous expression in limb E14.5 (RPKM 9.4), CNS E11.5 (RPKM 9.3) and 28 other tissues See more
Orthologs

Genomic context

See Virma in Genome Data Viewer
Location:
4; 4 A1
Exon count:
25
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 4 NC_000070.6 (11485949..11551143)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (11413105..11478290)

Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 35631 Neighboring gene predicted gene 11821 Neighboring gene predicted gene, 35693 Neighboring gene RAD54 homolog B (S. cerevisiae) Neighboring gene fibrinogen silencer binding protein

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

Pathways from BioSystems

  • mRNA processing, organism-specific biosystem (from WikiPathways)
    mRNA processing, organism-specific biosystemAdapted from Reactome, see: [http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_1675.1 REACT 1675.1] This process describes the conversion of precursor messenger RNA into mature messenge...

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by MGI

Process Evidence Code Pubs
RNA splicing IEA
Inferred from Electronic Annotation
more info
 
mRNA alternative polyadenylation ISO
Inferred from Sequence Orthology
more info
 
mRNA methylation ISO
Inferred from Sequence Orthology
more info
 
mRNA processing IEA
Inferred from Electronic Annotation
more info
 
multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
RNA N6-methyladenosine methyltransferase complex IDA
Inferred from Direct Assay
more info
PubMed 
RNA N6-methyladenosine methyltransferase complex ISO
Inferred from Sequence Orthology
more info
 
colocalizes_with RNA N6-methyladenosine methyltransferase complex ISO
Inferred from Sequence Orthology
more info
 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytosol ISO
Inferred from Sequence Orthology
more info
 
nuclear body ISO
Inferred from Sequence Orthology
more info
 
nuclear speck ISO
Inferred from Sequence Orthology
more info
 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081183.1NP_001074652.1  protein virilizer homolog isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AL732538, AL772170
    Consensus CDS
    CCDS38693.1
    UniProtKB/TrEMBL
    E9PZY8
    Related
    ENSMUSP00000103943.2, ENSMUST00000108307.2
    Conserved Domains (2) summary
    pfam15502
    Location:17521857
    MPLKIP; M-phase-specific PLK1-interacting protein
    pfam15912
    Location:5236
    VIR_N; Virilizer, N-terminal
  2. NM_001347055.1NP_001333984.1  protein virilizer homolog isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.
    Source sequence(s)
    AL732538, AL772170
    Consensus CDS
    CCDS84705.1
    UniProtKB/Swiss-Prot
    A2AIV2

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000070.6 Reference GRCm38.p4 C57BL/6J

    Range
    11485949..11551143
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006538160.3XP_006538223.1  protein virilizer homolog isoform X1

    Related
    ENSMUSP00000058078.6, ENSMUST00000059914.12
    Conserved Domains (2) summary
    pfam15502
    Location:17021807
    MPLKIP; M-phase-specific PLK1-interacting protein
    pfam15912
    Location:5236
    VIR_N; Virilizer, N-terminal
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