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Pop4 processing of precursor 4, ribonuclease P/MRP family, (S. cerevisiae) [ Mus musculus (house mouse) ]

Gene ID: 66161, updated on 9-May-2024

Summary

Official Symbol
Pop4provided by MGI
Official Full Name
processing of precursor 4, ribonuclease P/MRP family, (S. cerevisiae)provided by MGI
Primary source
MGI:MGI:1913411
See related
Ensembl:ENSMUSG00000030423 AllianceGenome:MGI:1913411
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Rpp29; 1110023P21Rik
Summary
Predicted to enable ribonuclease P RNA binding activity. Predicted to contribute to ribonuclease P activity. Predicted to be involved in rRNA processing and tRNA 5'-leader removal. Predicted to be located in nucleolus. Predicted to be part of multimeric ribonuclease P complex and ribonuclease MRP complex. Is expressed in sensory organ and skeleton. Orthologous to human POP4 (POP4 homolog, ribonuclease P/MRP subunit). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 23.9), CNS E14 (RPKM 20.3) and 26 other tissues See more
Orthologs
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Genomic context

See Pop4 in Genome Data Viewer
Location:
7 B3; 7 25.36 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (37962239..37970803, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (38262812..38271393, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA D530033B14 gene Neighboring gene RIKEN cDNA 1600014C10 gene Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:38974627-38974780 Neighboring gene STARR-positive B cell enhancer ABC_E3714 Neighboring gene pleckstrin homology domain containing, family F (with FYVE domain) member 1 Neighboring gene STARR-seq mESC enhancer starr_18689 Neighboring gene STARR-seq mESC enhancer starr_18690 Neighboring gene STARR-seq mESC enhancer starr_18693 Neighboring gene predicted gene 9220 Neighboring gene predicted gene 4451

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Targeted (1) 

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables ribonuclease P RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables ribonuclease P RNA binding ISO
Inferred from Sequence Orthology
more info
 
contributes_to ribonuclease P activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in RNA processing IEA
Inferred from Electronic Annotation
more info
 
involved_in rRNA processing IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in tRNA 5'-leader removal ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within tRNA processing IEA
Inferred from Electronic Annotation
more info
 
involved_in tRNA processing IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of multimeric ribonuclease P complex ISO
Inferred from Sequence Orthology
more info
 
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
part_of ribonuclease MRP complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of ribonuclease P complex IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
ribonuclease P protein subunit p29
Names
POP4 (processing of precursor , S. cerevisiae) homolog
NP_079666.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025390.5NP_079666.1  ribonuclease P protein subunit p29

    See identical proteins and their annotated locations for NP_079666.1

    Status: VALIDATED

    Source sequence(s)
    AC157552
    Consensus CDS
    CCDS39915.1
    UniProtKB/Swiss-Prot
    Q3U6V7, Q9CR08
    Related
    ENSMUSP00000032585.7, ENSMUST00000032585.8
    Conserved Domains (1) summary
    pfam01868
    Location:129211
    UPF0086; Domain of unknown function UPF0086

RNA

  1. NR_184804.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC157552
  2. NR_184805.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC157552

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    37962239..37970803 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)