Mrps36 mitochondrial ribosomal protein S36 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Mrps36provided by MGI
Official Full Name: mitochondrial ribosomal protein S36provided by MGI
Primary source: MGI:MGI:1913378
See related: Ensembl:ENSMUSG00000061474 AllianceGenome:MGI:1913378
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: S36mt; 1110018B13Rik
Summary: Predicted to be involved in 2-oxoglutarate metabolic process. Located in mitochondrion. Is expressed in several structures, including early conceptus; gonad; heart; liver; and metanephros. Orthologous to human MRPS36 (mitochondrial ribosomal protein S36). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in heart adult (RPKM 42.2), testis adult (RPKM 40.3) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 13; 13 D1

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
109	current	GRCm39 (GCF_000001635.27)	13	NC_000079.7 (100872448..100881167, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	13	NC_000079.6 (100735940..100744659, complement)

Chromosome 13 - NC_000079.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

NoName (e-PCR)
- UniSTS:488726

D13Mit195 (e-PCR), detects polymorphism
- UniSTS:127015

Homology

Homologs of the Mrps36 gene: The Mrps36 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, rat, chicken, zebrafish, and frog.
Orthologs from Annotation Pipeline: 495 organisms have orthologs with human gene Mrps36
Orthologs

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
contributes_to oxoglutarate dehydrogenase (succinyl-transferring) activity	IBA Inferred from Biological aspect of Ancestor more info	PubMed

Process	Evidence Code	Pubs
involved_in 2-oxoglutarate metabolic process	IBA Inferred from Biological aspect of Ancestor more info	PubMed
involved_in 2-oxoglutarate metabolic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in tricarboxylic acid cycle	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
part_of mitochondrial oxoglutarate dehydrogenase complex	IBA Inferred from Biological aspect of Ancestor more info	PubMed
part_of mitochondrial oxoglutarate dehydrogenase complex	IMP Inferred from Mutant Phenotype more info	PubMed
located_in mitochondrion	HDA more info	PubMed
located_in mitochondrion	IDA Inferred from Direct Assay more info	PubMed
located_in mitochondrion	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: alpha-ketoglutarate dehydrogenase component 4

Names: 28S ribosomal protein S36, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001190264.1 → NP_001177193.1 alpha-ketoglutarate dehydrogenase component 4 isoform 2

See identical proteins and their annotated locations for NP_001177193.1

Status: VALIDATED

Description

Transcript Variant: This variant (2) uses an alternate in-frame splice site in the coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1.

Source sequence(s)

AC165159, AK009966

Consensus CDS

CCDS49347.1

UniProtKB/TrEMBL

Q9D6T9

Related

ENSMUSP00000104954.2, ENSMUST00000078573.5
NM_025369.3 → NP_079645.1 alpha-ketoglutarate dehydrogenase component 4 isoform 1

See identical proteins and their annotated locations for NP_079645.1

Status: VALIDATED

Description

Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).

Source sequence(s)

AC165159, AK003765

Consensus CDS

CCDS36767.1

UniProtKB/Swiss-Prot

Q4VA25, Q9CQX8

UniProtKB/TrEMBL

A0A8C6G9W2

Related

ENSMUSP00000104957.2, ENSMUST00000109333.8