U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Tomm6 translocase of outer mitochondrial membrane 6 [ Mus musculus (house mouse) ]

Gene ID: 66119, updated on 27-Nov-2024

Summary

Official Symbol
Tomm6provided by MGI
Official Full Name
translocase of outer mitochondrial membrane 6provided by MGI
Primary source
MGI:MGI:1913369
See related
Ensembl:ENSMUSG00000033475 AllianceGenome:MGI:1913369
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1110002E23Rik
Summary
Predicted to be involved in protein transport. Located in mitochondrion. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; sensory organ; and thymus. Orthologous to human TOMM6 (translocase of outer mitochondrial membrane 6). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in placenta adult (RPKM 33.4), stomach adult (RPKM 30.0) and 28 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Tomm6 in Genome Data Viewer
Location:
17 C; 17 23.87 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (47997570..47999311, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (47686645..47688386, complement)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene cyclin D3 Neighboring gene STARR-positive B cell enhancer ABC_E9169 Neighboring gene bystin-like Neighboring gene predicted gene 20517 Neighboring gene STARR-positive B cell enhancer ABC_E10959 Neighboring gene mediator complex subunit 20 Neighboring gene Kpna2 retrotransposed pseudogene Neighboring gene ubiquitin specific peptidase 49 Neighboring gene STARR-positive B cell enhancer ABC_E4218 Neighboring gene prickle planar cell polarity protein 4 Neighboring gene translocase of outer mitochondrial membrane 6, opposite strand Neighboring gene fibroblast growth factor receptor substrate 3 Neighboring gene fibroblast growth factor receptor substrate 3, opposite strand

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of mitochondrial outer membrane translocase complex IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
mitochondrial import receptor subunit TOM6 homolog
Names
overexpressed breast tumor protein homolog
translocase of outer membrane 6 kDa subunit homolog
translocase of outer mitochondrial membrane 6 homolog

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001164729.1NP_001158201.1  mitochondrial import receptor subunit TOM6 homolog

    See identical proteins and their annotated locations for NP_001158201.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    BC089325, CA319049, CA321392
    Consensus CDS
    CCDS37643.1
    UniProtKB/Swiss-Prot
    Q9CQN3
    Related
    ENSMUSP00000108926.2, ENSMUST00000113301.2
    Conserved Domains (1) summary
    pfam15184
    Location:174
    TOM6p; Mitochondrial import receptor subunit TOM6 homolog
  2. NM_025365.3NP_079641.1  mitochondrial import receptor subunit TOM6 homolog

    See identical proteins and their annotated locations for NP_079641.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 3' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AK010470, BC089325, CA321392
    Consensus CDS
    CCDS37643.1
    UniProtKB/Swiss-Prot
    Q9CQN3
    Related
    ENSMUSP00000108927.4, ENSMUST00000113302.10
    Conserved Domains (1) summary
    pfam15184
    Location:174
    TOM6p; Mitochondrial import receptor subunit TOM6 homolog

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    47997570..47999311 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)