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Lamtor4 late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 [ Mus musculus (house mouse) ]

Gene ID: 66096, updated on 19-Mar-2019

Summary

Official Symbol
Lamtor4provided by MGI
Official Full Name
late endosomal/lysosomal adaptor, MAPK and MTOR activator 4provided by MGI
Primary source
MGI:MGI:1913346
See related
Ensembl:ENSMUSG00000050552
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AV006840; 0910001L09Rik
Expression
Ubiquitous expression in kidney adult (RPKM 118.3), genital fat pad adult (RPKM 111.8) and 28 other tissues See more
Orthologs

Genomic context

See Lamtor4 in Genome Data Viewer
Location:
5; 5 G2
Exon count:
4
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 5 NC_000071.6 (138255482..138259395)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (138696710..138700623)

Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene predicted gene 454 Neighboring gene neurexophilin and PC-esterase domain family, member 5 Neighboring gene RIKEN cDNA 6330418K02 gene Neighboring gene microtubule associated protein 11 Neighboring gene galactose-3-O-sulfotransferase 4 Neighboring gene stromal antigen 3

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
contributes_to guanyl-nucleotide exchange factor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
contributes_to guanyl-nucleotide exchange factor activity ISO
Inferred from Sequence Orthology
more info
 
contributes_to molecular adaptor activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
cellular response to amino acid stimulus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cellular response to amino acid stimulus ISO
Inferred from Sequence Orthology
more info
 
positive regulation of TOR signaling IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of TOR signaling ISO
Inferred from Sequence Orthology
more info
 
protein localization to lysosome ISO
Inferred from Sequence Orthology
more info
 
regulation of cell size ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
Ragulator complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Ragulator complex ISO
Inferred from Sequence Orthology
more info
 
intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
lysosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
lysosome ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
ragulator complex protein LAMTOR4
Names
UPF0539 protein C7orf59 homolog
late endosomal/lysosomal adaptor and MAPK and MTOR activator 4

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081108.2NP_001074577.1  ragulator complex protein LAMTOR4

    See identical proteins and their annotated locations for NP_001074577.1

    Status: VALIDATED

    Source sequence(s)
    BC056178, BC144958
    Consensus CDS
    CCDS39342.1
    UniProtKB/Swiss-Prot
    Q8CF66
    Related
    ENSMUSP00000056693.6, ENSMUST00000062067.7

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000071.6 Reference GRCm38.p4 C57BL/6J

    Range
    138255482..138259395
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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