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Atp5d ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit [ Mus musculus (house mouse) ]

Gene ID: 66043, updated on 5-Aug-2022

Summary

Official Symbol
Atp5dprovided by MGI
Official Full Name
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunitprovided by MGI
Primary source
MGI:MGI:1913293
See related
Ensembl:ENSMUSG00000003072 AllianceGenome:MGI:1913293
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
C85518; Atp5f1d; AA960090; AI876556; AU020773; 0610008F14Rik; 1500000I11Rik
Summary
Predicted to enable proton transmembrane transporter activity. Predicted to contribute to ATP hydrolysis activity and proton-transporting ATP synthase activity, rotational mechanism. Predicted to be involved in mitochondrial ATP synthesis coupled proton transport and mitochondrial proton-transporting ATP synthase complex assembly. Predicted to act upstream of or within proton transmembrane transport. Located in mitochondrial inner membrane. Is expressed in several structures, including alimentary system; eye; genitourinary system; integumental system; and nervous system. Human ortholog(s) of this gene implicated in mitochondrial complex V (ATP synthase) deficiency. Orthologous to human ATP5F1D (ATP synthase F1 subunit delta). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in duodenum adult (RPKM 1424.1), adrenal adult (RPKM 1222.1) and 23 other tissues See more
Orthologs
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Genomic context

See Atp5d in Genome Data Viewer
Location:
10; 10 C1
Exon count:
9
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (79974451..79981662)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (80138698..80145828)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (79605060..79608563)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene strawberry notch 2 Neighboring gene serine/threonine kinase 11 Neighboring gene calcium channel, voltage-dependent, beta subunit associated regulatory protein Neighboring gene midnolin Neighboring gene cold inducible RNA binding protein

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
contributes_to ATP hydrolysis activity ISO
Inferred from Sequence Orthology
more info
 
enables protein-containing complex binding ISO
Inferred from Sequence Orthology
more info
 
enables proton transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
contributes_to proton-transporting ATP synthase activity, rotational mechanism ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
ATP synthase subunit delta, mitochondrial
Names
ATP synthase F1 subunit delta
F-ATPase delta subunit
NP_001334021.1
NP_079589.2
XP_017169541.1
XP_030101070.1
XP_030101071.1
XP_030101072.1
XP_030101073.1
XP_036011835.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001347092.1NP_001334021.1  ATP synthase subunit delta, mitochondrial isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    BE951291, BM948933, CX200198
    Consensus CDS
    CCDS83726.1
    UniProtKB/TrEMBL
    D3Z7S4
    Related
    ENSMUSP00000101005.2, ENSMUST00000105366.2
    Conserved Domains (1) summary
    cd12152
    Location:3898
    F1-ATPase_delta; mitochondrial ATP synthase delta subunit
  2. NM_025313.2NP_079589.2  ATP synthase subunit delta, mitochondrial isoform 1 precursor

    See identical proteins and their annotated locations for NP_079589.2

    Status: VALIDATED

    Source sequence(s)
    AA409366, AK151151, BY451544
    Consensus CDS
    CCDS24010.1
    UniProtKB/Swiss-Prot
    Q9D3D9
    UniProtKB/TrEMBL
    Q4FK74
    Related
    ENSMUSP00000003156.9, ENSMUST00000003156.15
    Conserved Domains (1) summary
    cd12152
    Location:38162
    F1-ATPase_delta; mitochondrial ATP synthase delta subunit

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    79974451..79981662
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017314052.3XP_017169541.1  ATP synthase subunit delta, mitochondrial isoform X1

    UniProtKB/Swiss-Prot
    Q9D3D9
    UniProtKB/TrEMBL
    Q4FK74
    Conserved Domains (1) summary
    cd12152
    Location:38162
    F1-ATPase_delta; mitochondrial ATP synthase delta subunit
  2. XM_030245212.2XP_030101072.1  ATP synthase subunit delta, mitochondrial isoform X1

    UniProtKB/Swiss-Prot
    Q9D3D9
    Conserved Domains (1) summary
    cd12152
    Location:38162
    F1-ATPase_delta; mitochondrial ATP synthase delta subunit
  3. XM_030245213.2XP_030101073.1  ATP synthase subunit delta, mitochondrial isoform X2

    Conserved Domains (1) summary
    cd12152
    Location:3898
    F1-ATPase_delta; mitochondrial ATP synthase delta subunit
  4. XM_036155942.1XP_036011835.1  ATP synthase subunit delta, mitochondrial isoform X1

    UniProtKB/Swiss-Prot
    Q9D3D9
    Conserved Domains (1) summary
    cd12152
    Location:38162
    F1-ATPase_delta; mitochondrial ATP synthase delta subunit
  5. XM_030245211.2XP_030101071.1  ATP synthase subunit delta, mitochondrial isoform X1

    UniProtKB/Swiss-Prot
    Q9D3D9
    Conserved Domains (1) summary
    cd12152
    Location:38162
    F1-ATPase_delta; mitochondrial ATP synthase delta subunit
  6. XM_030245210.2XP_030101070.1  ATP synthase subunit delta, mitochondrial isoform X1

    UniProtKB/Swiss-Prot
    Q9D3D9
    Related
    ENSMUSP00000101006.2, ENSMUST00000105367.8
    Conserved Domains (1) summary
    cd12152
    Location:38162
    F1-ATPase_delta; mitochondrial ATP synthase delta subunit