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RASL11B RAS like family 11 member B [ Homo sapiens (human) ]

Gene ID: 65997, updated on 13-Mar-2020

Summary

Official Symbol
RASL11Bprovided by HGNC
Official Full Name
RAS like family 11 member Bprovided by HGNC
Primary source
HGNC:HGNC:23804
See related
Ensembl:ENSG00000128045 MIM:612404
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
RASL11B is a member of the small GTPase protein family with a high degree of similarity to RAS (see HRAS, MIM 190020) proteins.[supplied by OMIM, Nov 2008]
Expression
Biased expression in ovary (RPKM 17.0), heart (RPKM 11.4) and 12 other tissues See more
Orthologs

Genomic context

See RASL11B in Genome Data Viewer
Location:
4q12
Exon count:
4
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 4 NC_000004.12 (52862317..52866835)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (53728495..53733002)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107986281 Neighboring gene endogenous retrovirus group MER34 member 1, envelope Neighboring gene long intergenic non-protein coding RNA 1618 Neighboring gene Sharpr-MPRA regulatory region 13979 Neighboring gene uncharacterized LOC101928658 Neighboring gene sec1 family domain containing 2 Neighboring gene VISTA enhancer hs1668

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC2827, MGC4499

Gene Ontology Provided by GOA

Function Evidence Code Pubs
GTP binding IEA
Inferred from Electronic Annotation
more info
 
GTPase activity IEA
Inferred from Electronic Annotation
more info
 
transforming growth factor beta receptor binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
negative regulation of transforming growth factor beta receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
ras-like protein family member 11B

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_023940.3NP_076429.1  ras-like protein family member 11B

    See identical proteins and their annotated locations for NP_076429.1

    Status: VALIDATED

    Source sequence(s)
    AC023154, BC001087
    Consensus CDS
    CCDS3490.1
    UniProtKB/Swiss-Prot
    Q9BPW5
    Related
    ENSP00000248706.3, ENST00000248706.5
    Conserved Domains (1) summary
    cd04146
    Location:35203
    RERG_RasL11_like; Ras-related and Estrogen-Regulated Growth inhibitor (RERG) and Ras-like 11 (RasL11)-like families

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p13 Primary Assembly

    Range
    52862317..52866835
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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