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CAPRIN2 caprin family member 2 [ Homo sapiens (human) ]

Gene ID: 65981, updated on 11-Jun-2021

Summary

Official Symbol
CAPRIN2provided by HGNC
Official Full Name
caprin family member 2provided by HGNC
Primary source
HGNC:HGNC:21259
See related
Ensembl:ENSG00000110888 MIM:610375
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
EEG1; EEG-1; C1QDC1; RNG140
Summary
The protein encoded by this gene may regulate the transport of mRNA. It may play a role in the differentiation of erythroblasts. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]
Expression
Ubiquitous expression in testis (RPKM 12.6), brain (RPKM 7.2) and 25 other tissues See more
Orthologs
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Genomic context

See CAPRIN2 in Genome Data Viewer
Location:
12p11.21
Exon count:
22
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 12 NC_000012.12 (30709552..30754951, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (30862487..30907885, complement)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105369720 Neighboring gene importin 8 Neighboring gene uncharacterized LOC645485 Neighboring gene long intergenic non-protein coding RNA 941

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ11391, FLJ22569, KIAA1873, MGC102894, MGC134847, MGC134848

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables signaling receptor binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in centrosome IDA
Inferred from Direct Assay
more info
 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
 
located_in mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
part_of receptor complex IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
caprin-2
Names
C1q domain-containing protein 1
RNA granule protein 140
cytoplasmic activation/proliferation-associated protein 2
gastric cancer multidrug resistance-associated protein

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_029557.2 RefSeqGene

    Range
    5001..49963
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001002259.3NP_001002259.1  caprin-2 isoform 1

    See identical proteins and their annotated locations for NP_001002259.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (1). This variant is supported by BK001102.1, which is a third party annotation described in PMID:14764709.
    Source sequence(s)
    AC010198, AK021453, AL834212, AY074490, AY074491, BC025420, BQ010043, KF455635
    UniProtKB/Swiss-Prot
    Q6IMN6
    Conserved Domains (3) summary
    pfam05483
    Location:88540
    SCP-1; Synaptonemal complex protein 1 (SCP-1)
    pfam00386
    Location:9991124
    C1q; C1q domain
    pfam12287
    Location:628929
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
  2. NM_001206856.3NP_001193785.1  caprin-2 isoform 4

    See identical proteins and their annotated locations for NP_001193785.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) lacks an alternate in-frame exon and uses an alternate in-frame splice site in the central coding region, and uses an alternate splice site in the 3' coding region that causes a frameshift, compared to variant 1. The encoded isoform (4) has a distinct C-terminus and is shorter than isoform 1.
    Source sequence(s)
    AC010198, BC007520, BC117673, BR000870, KF455635
    Consensus CDS
    CCDS55816.1
    UniProtKB/Swiss-Prot
    Q6IMN6
    Related
    ENSP00000379150.2, ENST00000395805.6
    Conserved Domains (2) summary
    pfam05483
    Location:88510
    SCP-1; Synaptonemal complex protein 1 (SCP-1)
    pfam12287
    Location:628873
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
  3. NM_001319842.2NP_001306771.1  caprin-2 isoform 5

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) lacks an exon in the 5' region, initiates translation at a downstream start codon, and uses an alternate in-frame splice site in the central coding region, compared to variant 1. The encoded isoform (5) has a shorter N-terminus and is shorter than isoform 1.
    Source sequence(s)
    AC010198, AY074491, KF455635
    UniProtKB/Swiss-Prot
    Q6IMN6
    Conserved Domains (2) summary
    pfam00386
    Location:665790
    C1q; C1q domain
    pfam12287
    Location:287601
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
  4. NM_001319843.2NP_001306772.1  caprin-2 isoform 6

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) uses an alternate in-frame splice site in the central coding region compared to variant 1. The encoded isoform (6) is shorter than isoform 1. This variant is supported by BK001102.1, which is a third party annotation described in PMID:14764709.
    Source sequence(s)
    AC010198, BK001103, BR000870
    UniProtKB/Swiss-Prot
    Q6IMN6
    Conserved Domains (3) summary
    pfam05483
    Location:88510
    SCP-1; Synaptonemal complex protein 1 (SCP-1)
    pfam00386
    Location:9981123
    C1q; C1q domain
    pfam12287
    Location:628928
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
  5. NM_001319844.2NP_001306773.1  caprin-2 isoform 7

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7) differs in the 5' UTR, lacks a portion of the 5' coding region, initiates translation at a downstream start codon, and lacks an in-frame exon in the central coding region, compared to variant 1. The encoded isoform (7) has a shorter N-terminus and is shorter than isoform 1.
    Source sequence(s)
    AC010198
    Conserved Domains (5) summary
    PTZ00449
    Location:332673
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    pfam00386
    Location:8831008
    C1q; C1q domain
    pfam12287
    Location:539819
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam13870
    Location:45138
    DUF4201; Domain of unknown function (DUF4201)
    pfam18293
    Location:119234
    Caprin-1_dimer; Caprin-1 dimerization domain
  6. NM_001319845.2NP_001306774.1  caprin-2 isoform 8

    Status: REVIEWED

    Description
    Transcript Variant: This variant (8) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (8) has a shorter N-terminus than isoform 1. Variants 8 and 9 encode the same isoform (8).
    Source sequence(s)
    AC010198
    Conserved Domains (4) summary
    PTZ00121
    Location:49488
    PTZ00121; MAEBL; Provisional
    pfam00386
    Location:9181043
    C1q; C1q domain
    pfam12287
    Location:539854
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119234
    Caprin-1_dimer; Caprin-1 dimerization domain
  7. NM_001319846.2NP_001306775.1  caprin-2 isoform 8

    Status: REVIEWED

    Description
    Transcript Variant: This variant (9) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (8) has a shorter N-terminus than isoform 1. Variants 8 and 9 encode the same isoform (8).
    Source sequence(s)
    AC010198
    Conserved Domains (4) summary
    PTZ00121
    Location:49488
    PTZ00121; MAEBL; Provisional
    pfam00386
    Location:9181043
    C1q; C1q domain
    pfam12287
    Location:539854
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119234
    Caprin-1_dimer; Caprin-1 dimerization domain
  8. NM_001385498.1NP_001372427.1  caprin-2 isoform 9

    Status: REVIEWED

    Source sequence(s)
    AC010198, KF455635
    Conserved Domains (4) summary
    PTZ00121
    Location:130569
    PTZ00121; MAEBL; Provisional
    pfam00386
    Location:9781103
    C1q; C1q domain
    pfam12287
    Location:620914
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:200315
    Caprin-1_dimer; Caprin-1 dimerization domain
  9. NM_001385499.1NP_001372428.1  caprin-2 isoform 10

    Status: REVIEWED

    Source sequence(s)
    AC010198, KF455635
    Conserved Domains (5) summary
    PTZ00449
    Location:413754
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    COG0419
    Location:76258
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    pfam00386
    Location:9641089
    C1q; C1q domain
    pfam12287
    Location:620900
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:200315
    Caprin-1_dimer; Caprin-1 dimerization domain
  10. NM_001385500.1NP_001372429.1  caprin-2 isoform 11

    Status: REVIEWED

    Source sequence(s)
    AC010198, KF455635
    Conserved Domains (5) summary
    PTZ00449
    Location:413754
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    COG0419
    Location:76258
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    pfam00386
    Location:9631088
    C1q; C1q domain
    pfam12287
    Location:620899
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:200315
    Caprin-1_dimer; Caprin-1 dimerization domain
  11. NM_001385501.1NP_001372430.1  caprin-2 isoform 8

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (4) summary
    PTZ00121
    Location:49488
    PTZ00121; MAEBL; Provisional
    pfam00386
    Location:9181043
    C1q; C1q domain
    pfam12287
    Location:539854
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119234
    Caprin-1_dimer; Caprin-1 dimerization domain
  12. NM_001385502.1NP_001372431.1  caprin-2 isoform 12

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (4) summary
    PTZ00121
    Location:49488
    PTZ00121; MAEBL; Provisional
    pfam00386
    Location:9171042
    C1q; C1q domain
    pfam12287
    Location:539853
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119234
    Caprin-1_dimer; Caprin-1 dimerization domain
  13. NM_001385503.1NP_001372432.1  caprin-2 isoform 12

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (4) summary
    PTZ00121
    Location:49488
    PTZ00121; MAEBL; Provisional
    pfam00386
    Location:9171042
    C1q; C1q domain
    pfam12287
    Location:539853
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119234
    Caprin-1_dimer; Caprin-1 dimerization domain
  14. NM_001385504.1NP_001372433.1  caprin-2 isoform 13

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (4) summary
    PTZ00121
    Location:49488
    PTZ00121; MAEBL; Provisional
    pfam00386
    Location:8971022
    C1q; C1q domain
    pfam12287
    Location:539833
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119234
    Caprin-1_dimer; Caprin-1 dimerization domain
  15. NM_001385505.1NP_001372434.1  caprin-2 isoform 13

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (4) summary
    PTZ00121
    Location:49488
    PTZ00121; MAEBL; Provisional
    pfam00386
    Location:8971022
    C1q; C1q domain
    pfam12287
    Location:539833
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119234
    Caprin-1_dimer; Caprin-1 dimerization domain
  16. NM_001385506.1NP_001372435.1  caprin-2 isoform 13

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (4) summary
    PTZ00121
    Location:49488
    PTZ00121; MAEBL; Provisional
    pfam00386
    Location:8971022
    C1q; C1q domain
    pfam12287
    Location:539833
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119234
    Caprin-1_dimer; Caprin-1 dimerization domain
  17. NM_001385507.1NP_001372436.1  caprin-2 isoform 7

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (5) summary
    PTZ00449
    Location:332673
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    pfam00386
    Location:8831008
    C1q; C1q domain
    pfam12287
    Location:539819
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam13870
    Location:45138
    DUF4201; Domain of unknown function (DUF4201)
    pfam18293
    Location:119234
    Caprin-1_dimer; Caprin-1 dimerization domain
  18. NM_001385508.1NP_001372437.1  caprin-2 isoform 14

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (5) summary
    PTZ00449
    Location:332673
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    pfam00386
    Location:8821007
    C1q; C1q domain
    pfam12287
    Location:539818
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam13870
    Location:45138
    DUF4201; Domain of unknown function (DUF4201)
    pfam18293
    Location:119234
    Caprin-1_dimer; Caprin-1 dimerization domain
  19. NM_001385509.1NP_001372438.1  caprin-2 isoform 14

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (5) summary
    PTZ00449
    Location:332673
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    pfam00386
    Location:8821007
    C1q; C1q domain
    pfam12287
    Location:539818
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam13870
    Location:45138
    DUF4201; Domain of unknown function (DUF4201)
    pfam18293
    Location:119234
    Caprin-1_dimer; Caprin-1 dimerization domain
  20. NM_001385510.1NP_001372439.1  caprin-2 isoform 15

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (4) summary
    PTZ00449
    Location:332673
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    pfam00386
    Location:862987
    C1q; C1q domain
    pfam12287
    Location:539798
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119234
    Caprin-1_dimer; Caprin-1 dimerization domain
  21. NM_001385511.1NP_001372440.1  caprin-2 isoform 16

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (4) summary
    PTZ00121
    Location:49488
    PTZ00121; MAEBL; Provisional
    pfam00386
    Location:834959
    C1q; C1q domain
    pfam12287
    Location:539770
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119234
    Caprin-1_dimer; Caprin-1 dimerization domain
  22. NM_001385512.1NP_001372441.1  caprin-2 isoform 16

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (4) summary
    PTZ00121
    Location:49488
    PTZ00121; MAEBL; Provisional
    pfam00386
    Location:834959
    C1q; C1q domain
    pfam12287
    Location:539770
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119234
    Caprin-1_dimer; Caprin-1 dimerization domain
  23. NM_001385513.1NP_001372442.1  caprin-2 isoform 16

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (4) summary
    PTZ00121
    Location:49488
    PTZ00121; MAEBL; Provisional
    pfam00386
    Location:834959
    C1q; C1q domain
    pfam12287
    Location:539770
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119234
    Caprin-1_dimer; Caprin-1 dimerization domain
  24. NM_001385514.1NP_001372443.1  caprin-2 isoform 17

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (4) summary
    PTZ00121
    Location:49488
    PTZ00121; MAEBL; Provisional
    pfam00386
    Location:833958
    C1q; C1q domain
    pfam12287
    Location:539769
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119234
    Caprin-1_dimer; Caprin-1 dimerization domain
  25. NM_001385515.1NP_001372444.1  caprin-2 isoform 17

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (4) summary
    PTZ00121
    Location:49488
    PTZ00121; MAEBL; Provisional
    pfam00386
    Location:833958
    C1q; C1q domain
    pfam12287
    Location:539769
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119234
    Caprin-1_dimer; Caprin-1 dimerization domain
  26. NM_001385516.1NP_001372445.1  caprin-2 isoform 17

    Status: REVIEWED

    Source sequence(s)
    AC010198, KF455635
    Conserved Domains (3) summary
    PTZ00121
    Location:321569
    PTZ00121; MAEBL; Provisional
    pfam12287
    Location:620935
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:200315
    Caprin-1_dimer; Caprin-1 dimerization domain
  27. NM_001385518.1NP_001372447.1  caprin-2 isoform 18

    Status: REVIEWED

    Source sequence(s)
    AC010198, KF455635
    Conserved Domains (3) summary
    PTZ00121
    Location:321569
    PTZ00121; MAEBL; Provisional
    pfam12287
    Location:620935
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:200315
    Caprin-1_dimer; Caprin-1 dimerization domain
  28. NM_001385519.1NP_001372448.1  caprin-2 isoform 19

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (3) summary
    PTZ00121
    Location:240488
    PTZ00121; MAEBL; Provisional
    pfam12287
    Location:539854
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119234
    Caprin-1_dimer; Caprin-1 dimerization domain
  29. NM_001385520.1NP_001372449.1  caprin-2 isoform 19

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (3) summary
    PTZ00121
    Location:240488
    PTZ00121; MAEBL; Provisional
    pfam12287
    Location:539854
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119234
    Caprin-1_dimer; Caprin-1 dimerization domain
  30. NM_001385521.1NP_001372450.1  caprin-2 isoform 20

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (3) summary
    PTZ00121
    Location:240488
    PTZ00121; MAEBL; Provisional
    pfam12287
    Location:539853
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119234
    Caprin-1_dimer; Caprin-1 dimerization domain
  31. NM_001385522.1NP_001372451.1  caprin-2 isoform 20

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (3) summary
    PTZ00121
    Location:240488
    PTZ00121; MAEBL; Provisional
    pfam12287
    Location:539853
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119234
    Caprin-1_dimer; Caprin-1 dimerization domain
  32. NM_001385523.1NP_001372452.1  caprin-2 isoform 21

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (3) summary
    PTZ00121
    Location:240488
    PTZ00121; MAEBL; Provisional
    pfam12287
    Location:539833
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119234
    Caprin-1_dimer; Caprin-1 dimerization domain
  33. NM_001385524.1NP_001372453.1  caprin-2 isoform 21

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (3) summary
    PTZ00121
    Location:240488
    PTZ00121; MAEBL; Provisional
    pfam12287
    Location:539833
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119234
    Caprin-1_dimer; Caprin-1 dimerization domain
  34. NM_001385525.1NP_001372454.1  caprin-2 isoform 21

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Related
    ENSP00000438010.1, ENST00000537108.5
    Conserved Domains (3) summary
    PTZ00121
    Location:240488
    PTZ00121; MAEBL; Provisional
    pfam12287
    Location:539833
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119234
    Caprin-1_dimer; Caprin-1 dimerization domain
  35. NM_001385526.1NP_001372455.1  caprin-2 isoform 22

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (3) summary
    PTZ00449
    Location:332673
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    pfam12287
    Location:539798
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119234
    Caprin-1_dimer; Caprin-1 dimerization domain
  36. NM_001385527.1NP_001372456.1  caprin-2 isoform 23

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (3) summary
    PTZ00121
    Location:240488
    PTZ00121; MAEBL; Provisional
    pfam12287
    Location:539770
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119234
    Caprin-1_dimer; Caprin-1 dimerization domain
  37. NM_001385528.1NP_001372457.1  caprin-2 isoform 24

    Status: REVIEWED

    Source sequence(s)
    AC010198, KF455635
    Conserved Domains (2) summary
    pfam00386
    Location:666791
    C1q; C1q domain
    pfam12287
    Location:287602
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
  38. NM_001385529.1NP_001372458.1  caprin-2 isoform 24

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (2) summary
    pfam00386
    Location:666791
    C1q; C1q domain
    pfam12287
    Location:287602
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
  39. NM_001385531.1NP_001372460.1  caprin-2 isoform 5

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (2) summary
    pfam00386
    Location:665790
    C1q; C1q domain
    pfam12287
    Location:287601
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
  40. NM_001385532.1NP_001372461.1  caprin-2 isoform 5

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (2) summary
    pfam00386
    Location:665790
    C1q; C1q domain
    pfam12287
    Location:287601
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
  41. NM_001385533.1NP_001372462.1  caprin-2 isoform 5

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (2) summary
    pfam00386
    Location:665790
    C1q; C1q domain
    pfam12287
    Location:287601
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
  42. NM_001385534.1NP_001372463.1  caprin-2 isoform 5

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (2) summary
    pfam00386
    Location:665790
    C1q; C1q domain
    pfam12287
    Location:287601
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
  43. NM_001385535.1NP_001372464.1  caprin-2 isoform 25

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (3) summary
    PTZ00121
    Location:240488
    PTZ00121; MAEBL; Provisional
    pfam12287
    Location:539749
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    pfam18293
    Location:119234
    Caprin-1_dimer; Caprin-1 dimerization domain
  44. NM_001385537.1NP_001372466.1  caprin-2 isoform 26

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (2) summary
    pfam00386
    Location:645770
    C1q; C1q domain
    pfam12287
    Location:287581
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
  45. NM_001385538.1NP_001372467.1  caprin-2 isoform 27

    Status: REVIEWED

    Source sequence(s)
    AC010198, KF455635
    Conserved Domains (3) summary
    PTZ00121
    Location:7193
    PTZ00121; MAEBL; Provisional
    pfam00386
    Location:642767
    C1q; C1q domain
    pfam12287
    Location:264578
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
  46. NM_001385539.1NP_001372468.1  caprin-2 isoform 28

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (3) summary
    PTZ00449
    Location:80421
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    pfam00386
    Location:631756
    C1q; C1q domain
    pfam12287
    Location:287567
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
  47. NM_001385540.1NP_001372469.1  caprin-2 isoform 29

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (3) summary
    PTZ00449
    Location:80421
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    pfam00386
    Location:630755
    C1q; C1q domain
    pfam12287
    Location:287566
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
  48. NM_001385541.1NP_001372470.1  caprin-2 isoform 29

    Status: REVIEWED

    Source sequence(s)
    AC010198, KF455635
    Conserved Domains (3) summary
    PTZ00449
    Location:80421
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    pfam00386
    Location:630755
    C1q; C1q domain
    pfam12287
    Location:287566
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
  49. NM_001385542.1NP_001372471.1  caprin-2 isoform 30

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (3) summary
    PTZ00449
    Location:80421
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    pfam00386
    Location:610735
    C1q; C1q domain
    pfam12287
    Location:287546
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
  50. NM_001385543.1NP_001372472.1  caprin-2 isoform 31

    Status: REVIEWED

    Source sequence(s)
    AC010198, KF455635
    Conserved Domains (3) summary
    PTZ00449
    Location:57398
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    pfam00386
    Location:608733
    C1q; C1q domain
    pfam12287
    Location:264544
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
  51. NM_001385544.1NP_001372473.1  caprin-2 isoform 32

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (3) summary
    PTZ00449
    Location:57398
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    pfam00386
    Location:607732
    C1q; C1q domain
    pfam12287
    Location:264543
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
  52. NM_001385545.1NP_001372474.1  caprin-2 isoform 33

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (3) summary
    PTZ00121
    Location:7236
    PTZ00121; MAEBL; Provisional
    pfam00386
    Location:581706
    C1q; C1q domain
    pfam12287
    Location:287517
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
  53. NM_001385546.1NP_001372475.1  caprin-2 isoform 34

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (3) summary
    PTZ00121
    Location:7193
    PTZ00121; MAEBL; Provisional
    pfam00386
    Location:559684
    C1q; C1q domain
    pfam12287
    Location:264495
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
  54. NM_001385547.1NP_001372476.1  caprin-2 isoform 35

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (2) summary
    PTZ00121
    Location:7236
    PTZ00121; MAEBL; Provisional
    pfam12287
    Location:287602
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
  55. NM_001385548.1NP_001372477.1  caprin-2 isoform 35

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (2) summary
    PTZ00121
    Location:7236
    PTZ00121; MAEBL; Provisional
    pfam12287
    Location:287602
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
  56. NM_001385549.1NP_001372478.1  caprin-2 isoform 35

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (2) summary
    PTZ00121
    Location:7236
    PTZ00121; MAEBL; Provisional
    pfam12287
    Location:287602
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
  57. NM_001385550.1NP_001372479.1  caprin-2 isoform 36

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Related
    ENSP00000415407.2, ENST00000433722.6
    Conserved Domains (2) summary
    PTZ00121
    Location:7236
    PTZ00121; MAEBL; Provisional
    pfam12287
    Location:287601
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
  58. NM_001385551.1NP_001372480.1  caprin-2 isoform 36

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (2) summary
    PTZ00121
    Location:7236
    PTZ00121; MAEBL; Provisional
    pfam12287
    Location:287601
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
  59. NM_001385552.1NP_001372481.1  caprin-2 isoform 36

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (2) summary
    PTZ00121
    Location:7236
    PTZ00121; MAEBL; Provisional
    pfam12287
    Location:287601
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
  60. NM_001385553.1NP_001372482.1  caprin-2 isoform 37

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (2) summary
    PTZ00121
    Location:7236
    PTZ00121; MAEBL; Provisional
    pfam12287
    Location:287581
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
  61. NM_001385554.1NP_001372483.1  caprin-2 isoform 36

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (2) summary
    PTZ00121
    Location:7236
    PTZ00121; MAEBL; Provisional
    pfam12287
    Location:287601
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
  62. NM_001385557.1NP_001372486.1  caprin-2 isoform 38

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (2) summary
    PTZ00449
    Location:122421
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    pfam12287
    Location:287548
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
  63. NM_001385559.1NP_001372488.1  caprin-2 isoform 26

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Conserved Domains (2) summary
    pfam00386
    Location:645770
    C1q; C1q domain
    pfam12287
    Location:287581
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
  64. NM_023925.5NP_076414.2  caprin-2 isoform 2

    See identical proteins and their annotated locations for NP_076414.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2, also known as EEGL) lacks an alternate in-frame exon and uses an alternate in-frame splice site in the central coding region, compared to variant 1, resulting in an isoform (2) that is shorter than isoform 1.
    Source sequence(s)
    AC010198, AK021453, AL834212, AY074490, AY074491, BC025420, BQ010043, KF455635
    Consensus CDS
    CCDS8720.1
    UniProtKB/Swiss-Prot
    Q6IMN6
    Related
    ENSP00000298892.5, ENST00000298892.9
    Conserved Domains (3) summary
    pfam05483
    Location:88510
    SCP-1; Synaptonemal complex protein 1 (SCP-1)
    pfam00386
    Location:9491074
    C1q; C1q domain
    pfam12287
    Location:628879
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
  65. NM_032156.5NP_115532.3  caprin-2 isoform 3

    See identical proteins and their annotated locations for NP_115532.3

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) uses an alternate in-frame splice site in the central coding region, and an alternate splice site in the 3' coding region that causes a frameshift, compared to variant 1. The encoded isoform (3) has a distinct C-terminus and is shorter than isoform 1.
    Source sequence(s)
    AC010198, BC007520, BC117672, BR000870, KF455635
    Consensus CDS
    CCDS41766.2
    UniProtKB/Swiss-Prot
    Q6IMN6
    Related
    ENSP00000391479.1, ENST00000417045.5
    Conserved Domains (2) summary
    pfam05483
    Location:88510
    SCP-1; Synaptonemal complex protein 1 (SCP-1)
    pfam12287
    Location:628928
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

RNA

  1. NR_169636.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC010198
  2. NR_169637.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC010198
  3. NR_169638.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC010198
  4. NR_169639.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC010198
  5. NR_169640.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC010198
    Related
    ENST00000548676.5
  6. NR_169641.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC010198
  7. NR_169643.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC010198

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p13 Primary Assembly

    Range
    30709552..30754951 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017019854.1XP_016875343.1  caprin-2 isoform X7

  2. XM_006719144.3XP_006719207.1  caprin-2 isoform X6

    Conserved Domains (3) summary
    pfam05483
    Location:88510
    SCP-1; Synaptonemal complex protein 1 (SCP-1)
    pfam00386
    Location:9151040
    C1q; C1q domain
    pfam12287
    Location:628845
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
  3. XM_017019851.1XP_016875340.1  caprin-2 isoform X4

  4. XM_017019865.1XP_016875354.1  caprin-2 isoform X20

  5. XM_006719147.3XP_006719210.1  caprin-2 isoform X19

    UniProtKB/Swiss-Prot
    Q6IMN6
    Conserved Domains (2) summary
    pfam05483
    Location:88510
    SCP-1; Synaptonemal complex protein 1 (SCP-1)
    pfam12287
    Location:628908
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
  6. XM_024449145.1XP_024304913.1  caprin-2 isoform X33

    Conserved Domains (3) summary
    pfam00386
    Location:561686
    C1q; C1q domain
    pfam10243
    Location:75328
    MIP-T3; Microtubule-binding protein MIP-T3
    pfam12287
    Location:287497
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
  7. XM_024449147.1XP_024304915.1  caprin-2 isoform X37

    Conserved Domains (2) summary
    pfam12287
    Location:287566
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    cl25751
    Location:122421
    DUF4045; Domain of unknown function (DUF4045)
  8. XM_024449146.1XP_024304914.1  caprin-2 isoform X36

    Conserved Domains (2) summary
    pfam12287
    Location:287567
    Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
    cl25751
    Location:122421
    DUF4045; Domain of unknown function (DUF4045)
  9. XM_017019862.1XP_016875351.1  caprin-2 isoform X15

  10. XM_017019860.1XP_016875349.1  caprin-2 isoform X13

  11. XM_017019863.1XP_016875352.1  caprin-2 isoform X16

  12. XM_017019864.1XP_016875353.1  caprin-2 isoform X17

RNA

  1. XR_931325.2 RNA Sequence

    Related
    ENST00000454014.6
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