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BRD9 bromodomain containing 9 [ Homo sapiens (human) ]

Gene ID: 65980, updated on 26-Jul-2021

Summary

Official Symbol
BRD9provided by HGNC
Official Full Name
bromodomain containing 9provided by HGNC
Primary source
HGNC:HGNC:25818
See related
Ensembl:ENSG00000028310 MIM:618465
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PRO9856; SMARCI2; LAVS3040
Expression
Ubiquitous expression in testis (RPKM 6.5), lymph node (RPKM 4.8) and 25 other tissues See more
Orthologs
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Genomic context

See BRD9 in Genome Data Viewer
Location:
5p15.33
Exon count:
23
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 5 NC_000005.10 (863735..892803, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (863850..892916, complement)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101928768 Neighboring gene zinc finger DHHC-type containing 11 Neighboring gene signal peptidase complex subunit 2 pseudogene 3 Neighboring gene thyroid hormone receptor interactor 13 Neighboring gene uncharacterized LOC100506688

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer.
GeneReviews: Not available

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ43530, DKFZp434D0711, DKFZp686L0539

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables lysine-acetylated histone binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables lysine-acetylated histone binding IDA
Inferred from Direct Assay
more info
PubMed 
enables nucleic acid binding NAS
Non-traceable Author Statement
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in chromatin organization IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
part_of SWI/SNF complex IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
bromodomain-containing protein 9
Names
rhabdomyosarcoma antigen MU-RMS-40.8
sarcoma antigen NY-SAR-29

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001009877.3NP_001009877.2  bromodomain-containing protein 9 isoform 2

    See identical proteins and their annotated locations for NP_001009877.2

    Status: VALIDATED

    Source sequence(s)
    AC122719
    Consensus CDS
    CCDS34128.2
    UniProtKB/Swiss-Prot
    Q9H8M2
    UniProtKB/TrEMBL
    B4DXI2
    Related
    ENSP00000419845.1, ENST00000483173.5
    Conserved Domains (2) summary
    pfam12024
    Location:221450
    DUF3512; Domain of unknown function (DUF3512)
    cl02556
    Location:102184
    Bromodomain; Bromodomain. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
  2. NM_001317951.2NP_001304880.1  bromodomain-containing protein 9 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AK023503, AK299157
    UniProtKB/Swiss-Prot
    Q9H8M2
    Conserved Domains (2) summary
    cd05513
    Location:24121
    Bromo_brd7_like; Bromodomain, brd7_like subgroup. The BRD7 gene encodes a nuclear protein that has been shown to inhibit cell growth and the progression of the cell cycle by regulating cell-cycle genes at the transcriptional level. BRD7 has been identified as a gene ...
    pfam12024
    Location:178407
    DUF3512; Domain of unknown function (DUF3512)
  3. NM_001375861.1NP_001362790.1  bromodomain-containing protein 9 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC122719
    Conserved Domains (2) summary
    cd05513
    Location:140237
    Bromo_brd7_like; Bromodomain, brd7_like subgroup. The BRD7 gene encodes a nuclear protein that has been shown to inhibit cell growth and the progression of the cell cycle by regulating cell-cycle genes at the transcriptional level. BRD7 has been identified as a gene ...
    pfam12024
    Location:294553
    DUF3512; Domain of unknown function (DUF3512)
  4. NM_001375862.1NP_001362791.1  bromodomain-containing protein 9 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC122719
    Conserved Domains (2) summary
    cd05513
    Location:140237
    Bromo_brd7_like; Bromodomain, brd7_like subgroup. The BRD7 gene encodes a nuclear protein that has been shown to inhibit cell growth and the progression of the cell cycle by regulating cell-cycle genes at the transcriptional level. BRD7 has been identified as a gene ...
    pfam12024
    Location:319544
    DUF3512; Domain of unknown function (DUF3512)
  5. NM_001375863.1NP_001362792.1  bromodomain-containing protein 9 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC122719
    Conserved Domains (2) summary
    cd05513
    Location:142239
    Bromo_brd7_like; Bromodomain, brd7_like subgroup. The BRD7 gene encodes a nuclear protein that has been shown to inhibit cell growth and the progression of the cell cycle by regulating cell-cycle genes at the transcriptional level. BRD7 has been identified as a gene ...
    pfam12024
    Location:296525
    DUF3512; Domain of unknown function (DUF3512)
  6. NM_001375877.1NP_001362806.1  bromodomain-containing protein 9 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AC122719
    Conserved Domains (2) summary
    cd05513
    Location:140237
    Bromo_brd7_like; Bromodomain, brd7_like subgroup. The BRD7 gene encodes a nuclear protein that has been shown to inhibit cell growth and the progression of the cell cycle by regulating cell-cycle genes at the transcriptional level. BRD7 has been identified as a gene ...
    pfam12024
    Location:294523
    DUF3512; Domain of unknown function (DUF3512)
  7. NM_001375878.1NP_001362807.1  bromodomain-containing protein 9 isoform 8

    Status: VALIDATED

    Source sequence(s)
    AC122719
    Conserved Domains (2) summary
    cd05513
    Location:142239
    Bromo_brd7_like; Bromodomain, brd7_like subgroup. The BRD7 gene encodes a nuclear protein that has been shown to inhibit cell growth and the progression of the cell cycle by regulating cell-cycle genes at the transcriptional level. BRD7 has been identified as a gene ...
    pfam12024
    Location:276505
    DUF3512; Domain of unknown function (DUF3512)
  8. NM_001375879.1NP_001362808.1  bromodomain-containing protein 9 isoform 9

    Status: VALIDATED

    Source sequence(s)
    AC122719
    Conserved Domains (2) summary
    cd05513
    Location:140237
    Bromo_brd7_like; Bromodomain, brd7_like subgroup. The BRD7 gene encodes a nuclear protein that has been shown to inhibit cell growth and the progression of the cell cycle by regulating cell-cycle genes at the transcriptional level. BRD7 has been identified as a gene ...
    pfam12024
    Location:273502
    DUF3512; Domain of unknown function (DUF3512)
  9. NM_023924.5NP_076413.3  bromodomain-containing protein 9 isoform 1

    See identical proteins and their annotated locations for NP_076413.3

    Status: VALIDATED

    Source sequence(s)
    AK023503, AK026830, AK299157
    Consensus CDS
    CCDS34127.2
    UniProtKB/Swiss-Prot
    Q9H8M2
    Related
    ENSP00000419765.1, ENST00000467963.6
    Conserved Domains (2) summary
    cd05513
    Location:140237
    Bromo_brd7_like; Bromodomain, brd7_like subgroup. The BRD7 gene encodes a nuclear protein that has been shown to inhibit cell growth and the progression of the cell cycle by regulating cell-cycle genes at the transcriptional level. BRD7 has been identified as a gene ...
    pfam12024
    Location:274503
    DUF3512; Domain of unknown function (DUF3512)

RNA

  1. NR_134296.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC122719, AW151055, BX648703
    Related
    ENST00000489816.5
  2. NR_164742.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC122719

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p13 Primary Assembly

    Range
    863735..892803 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024446199.1XP_024301967.1  bromodomain-containing protein 9 isoform X7

    Conserved Domains (2) summary
    cd05513
    Location:24121
    Bromo_brd7_like; Bromodomain, brd7_like subgroup. The BRD7 gene encodes a nuclear protein that has been shown to inhibit cell growth and the progression of the cell cycle by regulating cell-cycle genes at the transcriptional level. BRD7 has been identified as a gene ...
    pfam12024
    Location:158387
    DUF3512; Domain of unknown function (DUF3512)
  2. XM_024446197.1XP_024301965.1  bromodomain-containing protein 9 isoform X5

    Conserved Domains (2) summary
    cd05513
    Location:24121
    Bromo_brd7_like; Bromodomain, brd7_like subgroup. The BRD7 gene encodes a nuclear protein that has been shown to inhibit cell growth and the progression of the cell cycle by regulating cell-cycle genes at the transcriptional level. BRD7 has been identified as a gene ...
    pfam12024
    Location:178407
    DUF3512; Domain of unknown function (DUF3512)
  3. XM_024446198.1XP_024301966.1  bromodomain-containing protein 9 isoform X6

    Conserved Domains (2) summary
    pfam12024
    Location:100329
    DUF3512; Domain of unknown function (DUF3512)
    cl02556
    Location:163
    Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
  4. XM_024446200.1XP_024301968.1  bromodomain-containing protein 9 isoform X8

    Conserved Domains (2) summary
    pfam12024
    Location:120349
    DUF3512; Domain of unknown function (DUF3512)
    cl02556
    Location:163
    Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
  5. XM_024446195.1XP_024301963.1  bromodomain-containing protein 9 isoform X3

    Conserved Domains (2) summary
    cd05513
    Location:140237
    Bromo_brd7_like; Bromodomain, brd7_like subgroup. The BRD7 gene encodes a nuclear protein that has been shown to inhibit cell growth and the progression of the cell cycle by regulating cell-cycle genes at the transcriptional level. BRD7 has been identified as a gene ...
    pfam12024
    Location:294523
    DUF3512; Domain of unknown function (DUF3512)
  6. XM_024446194.1XP_024301962.1  bromodomain-containing protein 9 isoform X3

    Conserved Domains (2) summary
    cd05513
    Location:140237
    Bromo_brd7_like; Bromodomain, brd7_like subgroup. The BRD7 gene encodes a nuclear protein that has been shown to inhibit cell growth and the progression of the cell cycle by regulating cell-cycle genes at the transcriptional level. BRD7 has been identified as a gene ...
    pfam12024
    Location:294523
    DUF3512; Domain of unknown function (DUF3512)
  7. XM_024446196.1XP_024301964.1  bromodomain-containing protein 9 isoform X4

    Conserved Domains (2) summary
    cd05513
    Location:140237
    Bromo_brd7_like; Bromodomain, brd7_like subgroup. The BRD7 gene encodes a nuclear protein that has been shown to inhibit cell growth and the progression of the cell cycle by regulating cell-cycle genes at the transcriptional level. BRD7 has been identified as a gene ...
    pfam12024
    Location:294481
    DUF3512; Domain of unknown function (DUF3512)
  8. XM_006714494.3XP_006714557.1  bromodomain-containing protein 9 isoform X9

    Conserved Domains (2) summary
    cd05513
    Location:140237
    Bromo_brd7_like; Bromodomain, brd7_like subgroup. The BRD7 gene encodes a nuclear protein that has been shown to inhibit cell growth and the progression of the cell cycle by regulating cell-cycle genes at the transcriptional level. BRD7 has been identified as a gene ...
    pfam12024
    Location:294342
    DUF3512; Domain of unknown function (DUF3512)
  9. XM_017009780.1XP_016865269.1  bromodomain-containing protein 9 isoform X10

RNA

  1. XR_002956175.1 RNA Sequence

    Related
    ENST00000495265.5
  2. XR_002956174.1 RNA Sequence

  3. XR_002956172.1 RNA Sequence

  4. XR_002956173.1 RNA Sequence

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