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NCF1B neutrophil cytosolic factor 1B (pseudogene) [ Homo sapiens (human) ]

Gene ID: 654816, updated on 17-Jun-2024

Summary

Official Symbol
NCF1Bprovided by HGNC
Official Full Name
neutrophil cytosolic factor 1B (pseudogene)provided by HGNC
Primary source
HGNC:HGNC:32522
See related
Ensembl:ENSG00000290838 AllianceGenome:HGNC:32522
Gene type
pseudo
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
NCF-1B; SH3PXD1B
Summary
Predicted to enable superoxide-generating NADPH oxidase activator activity. Predicted to be involved in respiratory burst and superoxide anion generation. Predicted to be part of NADPH oxidase complex. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in bone marrow (RPKM 76.4), spleen (RPKM 37.7) and 9 other tissues See more
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Genomic context

See NCF1B in Genome Data Viewer
Location:
7q11.23
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (73220639..73235945)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (74420852..74436153)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (72634674..72649979)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene speedy/RINGO cell cycle regulator family member E10 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:72568113-72568885 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18244 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:72571197-72571900 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:72578487-72578990 Neighboring gene H3K27ac hESC enhancer GRCh37_chr7:74642901-74643515 Neighboring gene general transcription factor IIi pseudogene 4 Neighboring gene Williams-Beuren syndrome centromeric block B recombination region Neighboring gene PHB1 pseudogene 5 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:74598481-74598982 Neighboring gene H3K27ac hESC enhancer GRCh37_chr7:74591815-74592314 Neighboring gene H3K27ac hESC enhancer GRCh37_chr7:74591313-74591814 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:72632401-72632902 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18245 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:72661597-72662585 Neighboring gene GTF2I repeat domain containing 2 pseudogene 1 Neighboring gene H3K27ac hESC enhancer GRCh37_chr7:72698447-72699037 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:72711681-72712181 Neighboring gene POM121 transmembrane nucleoporin B (pseudogene) Neighboring gene NOP2/Sun RNA methyltransferase 5

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Markers

Other Names

  • putative SH3 and PX domain-containing protein 1B
  • putative neutrophil cytosol factor 1B

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables phosphatidylinositol binding IEA
Inferred from Electronic Annotation
more info
 
enables superoxide-generating NADPH oxidase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in respiratory burst IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in superoxide anion generation IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of NADPH oxidase complex IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_003186.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    BC080194
    Related
    ENST00000423083.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

    Range
    73220639..73235945
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060931.1 Alternate T2T-CHM13v2.0

    Range
    74420852..74436153
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)