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GATA6 GATA binding protein 6 [ Bos taurus (domestic cattle) ]

Gene ID: 654400, updated on 30-Jan-2025
Official Symbol
GATA6provided by VGNC
Official Full Name
GATA binding protein 6provided by VGNC
Primary source
VGNC:VGNC:56366
See related
EnsemblRapid:ENSBTAG00070025535
Gene type
protein coding
RefSeq status
MODEL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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See GATA6 in Genome Data Viewer
Location:
chromosome: 24
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 24 NC_037351.1 (34161968..34194339, complement)

Chromosome 24 - NC_037351.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC104970025 Neighboring gene uncharacterized LOC101904579 Neighboring gene uncharacterized LOC100336909 Neighboring gene uncharacterized LOC132343770

Genomic Sequence:
NC_037351.1 Chromosome 24 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Related articles in PubMed

  1. The expression of the nuclear receptors NR5A1 and NR5A2 and transcription factor GATA6 correlates with steroidogenic gene expression in the bovine corpus luteum. Taniguchi H, et al. Mol Reprod Dev, 2009 Sep. PMID 19455657
  2. Molecular evidence for a critical period in mural trophoblast development in bovine blastocysts. Degrelle SA, et al. Dev Biol, 2005 Dec 15. PMID 16289134
  3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. GATA4 and GATA6 mRNA and proteins could be detected in bovine corpus luteum (CL). GATA6 showed a marked decrease at the regressed luteal stage, like NR5A1, NR5A2, and the other steroidogenic markers.
    Title: The expression of the nuclear receptors NR5A1 and NR5A2 and transcription factor GATA6 correlates with steroidogenic gene expression in the bovine corpus luteum.
Submit: New GeneRIF Correction

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell fate commitment IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in epithelial cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
transcription factor GATA-6
Names
GATA-6

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RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037351.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    34161968..34194339 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002697727.4 → XP_002697773.3  transcription factor GATA-6

    UniProtKB/TrEMBL
    F1N1M2
    Related
    ENSBTAP00070034403.1, ENSBTAT00070057813.1
    Conserved Domains (2) summary
    cd00202
    Location:441 → 492
    ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    pfam05349
    Location:149 → 375
    GATA-N; GATA-type transcription activator, N-terminal

  2. XM_024984607.2 → XP_024840375.1  transcription factor GATA-6

    UniProtKB/TrEMBL
    F1N1M2
    Conserved Domains (2) summary
    cd00202
    Location:441 → 492
    ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    pfam05349
    Location:149 → 375
    GATA-N; GATA-type transcription activator, N-terminal
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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