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ZG16 zymogen granule protein 16 [ Homo sapiens (human) ]

Gene ID: 653808, updated on 5-Aug-2022

Summary

Official Symbol
ZG16provided by HGNC
Official Full Name
zymogen granule protein 16provided by HGNC
Primary source
HGNC:HGNC:30961
See related
Ensembl:ENSG00000174992 MIM:617311; AllianceGenome:HGNC:30961
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
JCLN; JCLN1; ZG16A
Summary
Predicted to enable carbohydrate binding activity and peptidoglycan binding activity. Predicted to be involved in protein transport. Predicted to act upstream of or within defense response to Gram-positive bacterium and suppression of symbiont entry into host. Located in Golgi lumen and collagen-containing extracellular matrix. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in colon (RPKM 333.1), small intestine (RPKM 82.8) and 1 other tissue See more
Orthologs
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Genomic context

See ZG16 in Genome Data Viewer
Location:
16p11.2
Exon count:
4
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (29778256..29782973)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (30060382..30065096)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (29789577..29794294)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124903673 Neighboring gene chromosome 16 open reading frame 54 Neighboring gene Sharpr-MPRA regulatory region 1439 Neighboring gene uncharacterized LOC124903675 Neighboring gene uncharacterized LOC105371167 Neighboring gene kinesin family member 22

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ43571, FLJ92276, MGC34820, MGC183567

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
 
enables peptidoglycan binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in defense response to Gram-positive bacterium IEA
Inferred from Electronic Annotation
more info
 
involved_in protein transport TAS
Traceable Author Statement
more info
PubMed 
involved_in suppression of symbiont entry into host IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in Golgi lumen IDA
Inferred from Direct Assay
more info
PubMed 
located_in collagen-containing extracellular matrix IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in mucus layer IEA
Inferred from Electronic Annotation
more info
 
located_in zymogen granule membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
zymogen granule membrane protein 16
Names
jacalin-like lectin domain containing
secretory lectin ZG16
zymogen granule protein 16 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_152338.4NP_689551.3  zymogen granule membrane protein 16 precursor

    Status: VALIDATED

    Source sequence(s)
    AC009133, KF456182
    Consensus CDS
    CCDS54000.1
    UniProtKB/Swiss-Prot
    B9EK72
    Related
    ENSP00000383563.4, ENST00000400752.6
    Conserved Domains (1) summary
    cd09611
    Location:36158
    Jacalin_ZG16_like; Jacalin-like lectin domain of the zymogen granule protein 16 and related proteins

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

    Range
    29778256..29782973
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060940.1 Alternate T2T-CHM13v2.0

    Range
    30060382..30065096
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)