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LGALS7B galectin 7B [ Homo sapiens (human) ]

Gene ID: 653499, updated on 23-Nov-2021

Summary

Official Symbol
LGALS7Bprovided by HGNC
Official Full Name
galectin 7Bprovided by HGNC
Primary source
HGNC:HGNC:34447
See related
Ensembl:ENSG00000178934 MIM:617139
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PI7; GAL7; Gal-7; HKL-14; LGALS7
Summary
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridization studies indicate that this lectin is specifically expressed in keratinocytes and found mainly in stratified squamous epithelium. A duplicate copy of this gene (GeneID:3963) is found adjacent to, but on the opposite strand on chromosome 19. [provided by RefSeq, Jul 2008]
Expression
Restricted expression toward skin (RPKM 506.8) See more
Orthologs
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Genomic context

See LGALS7B in Genome Data Viewer
Location:
19q13.2
Exon count:
4
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (38789200..38791754)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (39279840..39282394)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene actinin alpha 4 Neighboring gene calpain 12 Neighboring gene galectin 7 Neighboring gene RNA, U6 small nuclear 140, pseudogene Neighboring gene galectin 4

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC75149, MGC88745

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables carbohydrate binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables galactoside binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in extracellular exosome HDA PubMed 
located_in extracellular space TAS
Traceable Author Statement
more info
PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
galectin-7
Names
keratinocyte lectin 14
lectin galactoside-binding soluble 7
lectin, galactoside-binding, soluble, 7B
p53-induced gene 1 protein
p53-induced protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001042507.4NP_001035972.1  galectin-7

    See identical proteins and their annotated locations for NP_001035972.1

    Status: REVIEWED

    Source sequence(s)
    AC022144, AW015224, BC042911, L07769
    Consensus CDS
    CCDS42565.1
    UniProtKB/Swiss-Prot
    P47929
    Related
    ENSP00000313571.3, ENST00000314980.5
    Conserved Domains (1) summary
    smart00908
    Location:11133
    Gal-bind_lectin; Galactoside-binding lectin

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    38789200..38791754
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p13 PATCHES

Genomic

  1. NW_014040929.1 Reference GRCh38.p13 PATCHES

    Range
    198889..201436
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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