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SPAG11A sperm associated antigen 11A [ Homo sapiens (human) ]

Gene ID: 653423, updated on 10-Jul-2021

Summary

Official Symbol
SPAG11Aprovided by HGNC
Official Full Name
sperm associated antigen 11Aprovided by HGNC
Primary source
HGNC:HGNC:33342
See related
Ensembl:ENSG00000178287
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HE2; EDDM2A
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See SPAG11A in Genome Data Viewer
Location:
8p23.1
Exon count:
7
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 8 NC_000008.11 (7847923..7863797)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (7705530..7721319)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene defensin beta 106A Neighboring gene defensin beta 104A Neighboring gene defensin beta 103A Neighboring gene heat shock protein family D (Hsp60) member 1 pseudogene 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in antimicrobial humoral immune response mediated by antimicrobial peptide IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in defense response to bacterium IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
sperm-associated antigen 11A
Names
epididymal protein 2A
human epididymis-specific protein 2
sperm antigen HE2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081552.3NP_001075021.2  sperm-associated antigen 11A isoform 1 precursor

    Status: VALIDATED

    Source sequence(s)
    AC130365, AF168618, AF170797
    Consensus CDS
    CCDS43700.1
    UniProtKB/Swiss-Prot
    Q6PDA7
    UniProtKB/TrEMBL
    A0A0A0MR37
    Related
    ENSP00000316012.5, ENST00000326558.9
    Conserved Domains (1) summary
    pfam05324
    Location:872
    Sperm_Ag_HE2; Sperm antigen HE2
  2. NM_001363726.3NP_001350655.1  sperm-associated antigen 11A isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    AC130365
    Consensus CDS
    CCDS87575.1
    Related
    ENSP00000416991.2, ENST00000434307.6
    Conserved Domains (1) summary
    pfam05324
    Location:871
    Sperm_Ag_HE2; Sperm antigen HE2
  3. NM_001395484.1NP_001382413.1  sperm-associated antigen 11A isoform 3 precursor

    Status: VALIDATED

    Source sequence(s)
    AC130365

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p13 Primary Assembly

    Range
    7847923..7863797
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005272392.5XP_005272449.3  sperm-associated antigen 11A isoform X1

    Related
    ENSP00000382990.2, ENST00000400125.6
    Conserved Domains (1) summary
    pfam05324
    Location:874
    Sperm_Ag_HE2; Sperm antigen HE2
  2. XM_017013744.1XP_016869233.1  sperm-associated antigen 11A isoform X3

    UniProtKB/TrEMBL
    C9IZU7
    Related
    ENSP00000316648.5, ENST00000326625.5
  3. XM_017013745.1XP_016869234.1  sperm-associated antigen 11A isoform X4

    UniProtKB/TrEMBL
    C9JP82
    Related
    ENSP00000394885.2, ENST00000454911.6

Reference GRCh38.p13 PATCHES

Genomic

  1. NW_018654717.1 Reference GRCh38.p13 PATCHES

    Range
    755806..771611
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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