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FAM86B2 family with sequence similarity 86 member B2 [ Homo sapiens (human) ]

Gene ID: 653333, updated on 4-Jun-2020

Summary

Official Symbol
FAM86B2provided by HGNC
Official Full Name
family with sequence similarity 86 member B2provided by HGNC
Primary source
HGNC:HGNC:32222
See related
Ensembl:ENSG00000145002 MIM:616123
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in ovary (RPKM 3.0), thyroid (RPKM 3.0) and 25 other tissues See more

Genomic context

See FAM86B2 in Genome Data Viewer
Location:
8p23.1
Exon count:
8
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 8 NC_000008.11 (12425401..12436406, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (12283064..12293909, complement)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 66 member A Neighboring gene defensin beta 109A (pseudogene) Neighboring gene family with sequence similarity 90 member A25, pseudogene Neighboring gene ALG1 like 12, pseudogene Neighboring gene Sharpr-MPRA regulatory regions 5244/11724 and 13137 Neighboring gene uncharacterized LOC100506990 Neighboring gene defensin beta 109E (pseudogene)

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
protein-containing complex IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
putative protein N-methyltransferase FAM86B2
Names
protein FAM86B2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001137610.2NP_001131082.1  putative protein N-methyltransferase FAM86B2

    See identical proteins and their annotated locations for NP_001131082.1

    Status: VALIDATED

    Source sequence(s)
    AC087203
    Consensus CDS
    CCDS59092.1
    UniProtKB/Swiss-Prot
    P0C5J1
    Related
    ENSP00000262365.4, ENST00000262365.8
    Conserved Domains (2) summary
    pfam14904
    Location:697
    FAM86; Family of unknown function
    cl17173
    Location:135286
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

RNA

  1. NR_148876.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC087203
  2. NR_148877.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC087203
  3. NR_148878.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC087203

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p13 Primary Assembly

    Range
    12425401..12436406 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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