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UCA1 urothelial cancer associated 1 [ Homo sapiens (human) ]

Gene ID: 652995, updated on 12-Oct-2019

Summary

Official Symbol
UCA1provided by HGNC
Official Full Name
urothelial cancer associated 1provided by HGNC
Primary source
HGNC:HGNC:37126
See related
Ensembl:ENSG00000214049 MIM:617500
Gene type
ncRNA
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CUDR; UCAT1; LINC00178; NCRNA00178; onco-lncRNA-36
Summary
This gene produces a long non-coding RNA that was found to be upregulated in bladder cancer and plays a regulatory role in cell proliferation. This transcript regulates several genes, including CREB (cAMP responsive element binding protein). Expression of this transcript is regulated by CCAAT/enhancer-binding protein-alpha. [provided by RefSeq, Dec 2017]
Expression
Biased expression in gall bladder (RPKM 19.1), endometrium (RPKM 12.1) and 5 other tissues See more

Genomic context

See UCA1 in Genome Data Viewer
Location:
19p13.12
Exon count:
3
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (15828947..15836321)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (15939757..15947131)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 10 subfamily H member 1 Neighboring gene zinc finger protein 861, pseudogene Neighboring gene long intergenic non-protein coding RNA 1764 Neighboring gene uncharacterized LOC105369202 Neighboring gene C-type lectin domain family 4 member O Neighboring gene cytochrome P450 family 4 subfamily F member 36, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from BioSystems

General gene information

Markers

Other Names

  • cancer up-regulated drug resistant
  • long intergenic non-protein coding RNA 178
  • urothelial cancer associated 1 (non-protein coding)

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_015379.3 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AK092401, DQ343132, GU357550
    Related
    ENST00000644174.2

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20190905

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    15828947..15836321
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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