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Csnk1g2 casein kinase 1, gamma 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 65278, updated on 5-Sep-2021

Summary

Official Symbol
Csnk1g2provided by RGD
Official Full Name
casein kinase 1, gamma 2provided by RGD
Primary source
RGD:621407
See related
Ensembl:ENSRNOG00000018529
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
monomeric protein kinase; expressed only in testis [RGD, Feb 2006]
Expression
Biased expression in Testes (RPKM 166.6), Thymus (RPKM 138.5) and 9 other tissues See more
Orthologs
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Genomic context

See Csnk1g2 in Genome Data Viewer
Location:
7q11
Exon count:
13
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (9076739..9095082, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (11944957..11963268, complement)

Chromosome 7 - NC_051342.1Genomic Context describing neighboring genes Neighboring gene MAPK interacting serine/threonine kinase 2 Neighboring gene BTB domain containing 2 Neighboring gene secretory carrier membrane protein 4 Neighboring gene adenosine deaminase, tRNA-specific 3 Neighboring gene abhydrolase domain containing 17A, depalmitoylase

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables protein serine kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein serine/threonine kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables protein serine/threonine kinase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in Wnt signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in endocytosis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in peptidyl-serine phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in peptidyl-serine phosphorylation ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of canonical Wnt signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in protein autophosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in protein phosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cell cortex IEA
Inferred from Electronic Annotation
more info
 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
casein kinase I isoform gamma-2; casein kinase I
Names
CKI-gamma 2
NP_001029042.1
NP_075590.2
XP_006241063.1
XP_006241065.1
XP_008763352.1
XP_038935799.1
XP_038935800.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033870.1NP_001029042.1  casein kinase I isoform gamma-2 isoform 1

    See identical proteins and their annotated locations for NP_001029042.1

    Status: VALIDATED

    Source sequence(s)
    BC072533
    UniProtKB/Swiss-Prot
    Q62762
    Related
    ENSRNOP00000072196.1, ENSRNOT00000080342.1
    Conserved Domains (2) summary
    cd14126
    Location:45332
    STKc_CK1_gamma; Catalytic domain of the Serine/Threonine protein kinase, Casein Kinase 1 gamma
    pfam12605
    Location:332385
    CK1gamma_C; Casein kinase 1 gamma C terminal
  2. NM_023102.2NP_075590.2  casein kinase I isoform gamma-2 isoform 2

    See identical proteins and their annotated locations for NP_075590.2

    Status: VALIDATED

    Source sequence(s)
    BC072533, U22297
    UniProtKB/Swiss-Prot
    Q62762
    UniProtKB/TrEMBL
    A0A0H2UHQ2
    Related
    ENSRNOP00000025266.5, ENSRNOT00000025266.6
    Conserved Domains (2) summary
    cd14126
    Location:45331
    STKc_CK1_gamma; Catalytic domain of the Serine/Threonine protein kinase, Casein Kinase 1 gamma
    pfam12605
    Location:331384
    CK1gamma_C; Casein kinase 1 gamma C terminal

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051342.1 Reference mRatBN7.2 Primary Assembly

    Range
    9076739..9095082 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039079871.1XP_038935799.1  casein kinase I isoform X2

    Conserved Domains (2) summary
    cd14126
    Location:45331
    STKc_CK1_gamma; Catalytic domain of the Serine/Threonine protein kinase, Casein Kinase 1 gamma
    pfam12605
    Location:331384
    CK1gamma_C; Casein kinase 1 gamma C terminal
  2. XM_006241001.4XP_006241063.1  casein kinase I isoform X1

    See identical proteins and their annotated locations for XP_006241063.1

    Conserved Domains (3) summary
    COG0515
    Location:45355
    SPS1; Serine/threonine protein kinase [Signal transduction mechanisms]
    cd14126
    Location:45358
    STKc_CK1_gamma; Catalytic domain of the Serine/Threonine protein kinase, Casein Kinase 1 gamma
    pfam12605
    Location:358400
    CK1gamma_C; Casein kinase 1 gamma C terminal
  3. XM_008765130.3XP_008763352.1  casein kinase I isoform X1

    See identical proteins and their annotated locations for XP_008763352.1

    Conserved Domains (3) summary
    COG0515
    Location:45355
    SPS1; Serine/threonine protein kinase [Signal transduction mechanisms]
    cd14126
    Location:45358
    STKc_CK1_gamma; Catalytic domain of the Serine/Threonine protein kinase, Casein Kinase 1 gamma
    pfam12605
    Location:358400
    CK1gamma_C; Casein kinase 1 gamma C terminal
  4. XM_039079872.1XP_038935800.1  casein kinase I isoform X4

    Conserved Domains (2) summary
    cd14126
    Location:16283
    STKc_CK1_gamma; Catalytic domain of the Serine/Threonine protein kinase, Casein Kinase 1 gamma
    pfam12605
    Location:283336
    CK1gamma_C; Casein kinase 1 gamma C terminal
  5. XM_006241003.4XP_006241065.1  casein kinase I isoform X3

    Conserved Domains (3) summary
    COG0515
    Location:21281
    SPS1; Serine/threonine protein kinase [Signal transduction mechanisms]
    cd14126
    Location:16284
    STKc_CK1_gamma; Catalytic domain of the Serine/Threonine protein kinase, Casein Kinase 1 gamma
    pfam12605
    Location:284326
    CK1gamma_C; Casein kinase 1 gamma C terminal

RNA

  1. XR_005486719.1 RNA Sequence

  2. XR_593259.3 RNA Sequence

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