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RSRC2 arginine and serine rich coiled-coil 2 [ Homo sapiens (human) ]

Gene ID: 65117, updated on 24-Nov-2020

Summary

Official Symbol
RSRC2provided by HGNC
Official Full Name
arginine and serine rich coiled-coil 2provided by HGNC
Primary source
HGNC:HGNC:30559
See related
Ensembl:ENSG00000111011
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in bone marrow (RPKM 73.5), testis (RPKM 24.5) and 25 other tissues See more
Orthologs

Genomic context

See RSRC2 in Genome Data Viewer
Location:
12q24.31
Exon count:
15
Annotation release Status Assembly Chr Location
109.20201120 current GRCh38.p13 (GCF_000001405.39) 12 NC_000012.12 (122503454..122526999, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (122989190..123011560, complement)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene CAP-Gly domain containing linker protein 1 Neighboring gene CLIP1 antisense RNA 1 Neighboring gene zinc finger CCHC-type containing 8 Neighboring gene kinetochore associated 1 Neighboring gene microRNA 9902-1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
arginine/serine-rich coiled-coil protein 2
Names
arginine/serine-rich coiled-coil 2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_023012.6NP_075388.2  arginine/serine-rich coiled-coil protein 2

    See identical proteins and their annotated locations for NP_075388.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) is the shortest transcript but encodes a functional protein.
    Source sequence(s)
    AB212664, AC127002
    Consensus CDS
    CCDS31920.1
    UniProtKB/Swiss-Prot
    Q7L4I2
    Related
    ENSP00000330188.6, ENST00000331738.12
    Conserved Domains (1) summary
    pfam15477
    Location:354423
    SMAP; Small acidic protein family

RNA

  1. NR_036434.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) has an additional exon in the CDS compared to variant 1. The exon includes a premature stop codon, so this variant is a nonsense-mediated mRNA decay candidate and does not make a functional protein.
    Source sequence(s)
    AC127002, AK094465, BC008684
  2. NR_036435.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) has an additional exon and an additional segment in the CDS compared to variant 1. The exon includes a premature stop codon, so this variant is a nonsense-mediated mRNA decay candidate and does not make a functional protein.
    Source sequence(s)
    AC127002, DB081070
  3. NR_036436.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) has an additional segment in the CDS compared to variant 1. The segment includes a premature stop codon, so this variant is a nonsense-mediated mRNA decay candidate and does not make a functional protein.
    Source sequence(s)
    AB212664, AC127002, BX647884

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20201120

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p13 Primary Assembly

    Range
    122503454..122526999 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017019830.2XP_016875319.1  arginine/serine-rich coiled-coil protein 2 isoform X3

  2. XM_011538688.2XP_011536990.1  arginine/serine-rich coiled-coil protein 2 isoform X2

    Conserved Domains (1) summary
    pfam15477
    Location:342394
    SMAP; Small acidic protein family
  3. XM_005253601.2XP_005253658.1  arginine/serine-rich coiled-coil protein 2 isoform X1

    See identical proteins and their annotated locations for XP_005253658.1

    Conserved Domains (1) summary
    pfam15477
    Location:355424
    SMAP; Small acidic protein family
  4. XM_005253602.2XP_005253659.1  arginine/serine-rich coiled-coil protein 2 isoform X4

    Conserved Domains (1) summary
    pfam15477
    Location:307376
    SMAP; Small acidic protein family
  5. XM_017019831.1XP_016875320.1  arginine/serine-rich coiled-coil protein 2 isoform X4

    Conserved Domains (1) summary
    pfam15477
    Location:307376
    SMAP; Small acidic protein family
  6. XM_017019833.2XP_016875322.1  arginine/serine-rich coiled-coil protein 2 isoform X7

    UniProtKB/Swiss-Prot
    Q7L4I2
    Conserved Domains (1) summary
    pfam15477
    Location:122191
    SMAP; Small acidic protein family
  7. XM_005253604.2XP_005253661.1  arginine/serine-rich coiled-coil protein 2 isoform X5

    See identical proteins and their annotated locations for XP_005253661.1

    Conserved Domains (1) summary
    pfam15477
    Location:296365
    SMAP; Small acidic protein family
  8. XM_017019832.1XP_016875321.1  arginine/serine-rich coiled-coil protein 2 isoform X6

    UniProtKB/TrEMBL
    B3KMH4
    Conserved Domains (1) summary
    pfam15477
    Location:123192
    SMAP; Small acidic protein family
  9. XM_011538689.1XP_011536991.1  arginine/serine-rich coiled-coil protein 2 isoform X5

    See identical proteins and their annotated locations for XP_011536991.1

    Conserved Domains (1) summary
    pfam15477
    Location:296365
    SMAP; Small acidic protein family

RNA

  1. XR_001748845.2 RNA Sequence

  2. XR_001748844.2 RNA Sequence

  3. XR_001748848.2 RNA Sequence

  4. XR_002957370.1 RNA Sequence

    Related
    ENST00000532695.5
  5. XR_001748847.2 RNA Sequence

  6. XR_001748846.2 RNA Sequence

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_198261.2: Suppressed sequence

    Description
    NM_198261.2: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
  2. NM_198262.2: Suppressed sequence

    Description
    NM_198262.2: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
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