Arl6ip6 ADP-ribosylation factor-like 6 interacting protein 6 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Arl6ip6provided by MGI
Official Full Name: ADP-ribosylation factor-like 6 interacting protein 6provided by MGI
Primary source: MGI:MGI:1929507
See related: Ensembl:ENSMUSG00000026960 AllianceGenome:MGI:1929507
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Aip-6; 2310057C01Rik; 2610529A11Rik
Summary: Located in nuclear inner membrane. Is expressed in midbrain ventricular layer; olfactory cortex ventricular layer; olfactory epithelium; submandibular gland primordium; and telencephalon ventricular layer. Orthologous to human ARL6IP6 (ADP ribosylation factor like GTPase 6 interacting protein 6). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in testis adult (RPKM 18.5), CNS E11.5 (RPKM 11.8) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 2; 2 C1.1

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
109	current	GRCm39 (GCF_000001635.27)	2	NC_000068.8 (53082096..53109233)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	2	NC_000068.7 (53192084..53219221)

Chromosome 2 - NC_000068.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

ADP-ribosylation factor 6 negatively regulates dendritic spine formation.
Title: The small GTPase ADP-ribosylation factor 6 negatively regulates dendritic spine formation.

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (2)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Homologs of the Arl6ip6 gene: The Arl6ip6 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, rat, and frog.
Orthologs from Annotation Pipeline: 379 organisms have orthologs with human gene Arl6ip6
Orthologs

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in nuclear inner membrane	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: ADP-ribosylation factor-like protein 6-interacting protein 6

Names: ADP-ribosylation-like factor 6 interacting protein 6; ARL-6-interacting protein 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.