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PPP1R3G protein phosphatase 1 regulatory subunit 3G [ Homo sapiens (human) ]

Gene ID: 648791, updated on 23-Nov-2023

Summary

Official Symbol
PPP1R3Gprovided by HGNC
Official Full Name
protein phosphatase 1 regulatory subunit 3Gprovided by HGNC
Primary source
HGNC:HGNC:14945
See related
Ensembl:ENSG00000219607 MIM:619541; AllianceGenome:HGNC:14945
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to enable glycogen binding activity and protein phosphatase 1 binding activity. Predicted to be involved in regulation of glycogen biosynthetic process. Predicted to act upstream of or within glucose homeostasis; positive regulation of glycogen (starch) synthase activity; and positive regulation of glycogen biosynthetic process. Predicted to be located in cytoplasm. Predicted to be part of protein phosphatase type 1 complex. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See PPP1R3G in Genome Data Viewer
Location:
6p25.1
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (5085341..5089487)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (4954549..4958695)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (5085575..5089721)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124901248 Neighboring gene LYRM4 antisense RNA 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:5027971-5028470 Neighboring gene ReSE screen-validated silencer GRCh37_chr6:5031032-5031192 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr6:5044856-5046055 Neighboring gene LYR motif containing 4 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23899 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23900 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:5063575-5064076 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16866 Neighboring gene TFB2M pseudogene 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16867 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16868 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16869 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:5085857-5086546 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23901 Neighboring gene MPRA-validated peak5632 silencer Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:5130070-5130656 Neighboring gene Sharpr-MPRA regulatory region 2533 Neighboring gene microRNA 3691 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:5193017-5193524 Neighboring gene Sharpr-MPRA regulatory region 15549 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr6:5230418-5231617 Neighboring gene uncharacterized LOC124901249

Genomic regions, transcripts, and products

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables glycogen binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein phosphatase 1 binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in glucose homeostasis IEA
Inferred from Electronic Annotation
more info
 
involved_in glycogen biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of glycogen biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of glycogen biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of protein phosphatase type 1 complex IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
protein phosphatase 1 regulatory subunit 3G
Names
protein phosphatase 1, regulatory (inhibitor) subunit 3G
putative protein phosphatase 1 regulatory inhibitor subunit 3G

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001145115.3NP_001138587.1  protein phosphatase 1 regulatory subunit 3G

    See identical proteins and their annotated locations for NP_001138587.1

    Status: VALIDATED

    Source sequence(s)
    AL035653, KF458078
    Consensus CDS
    CCDS47366.1
    UniProtKB/Swiss-Prot
    B7ZBB8
    Related
    ENSP00000393832.2, ENST00000405617.4
    Conserved Domains (1) summary
    pfam03370
    Location:212349
    CBM_21; Carbohydrate/starch-binding module (family 21)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

    Range
    5085341..5089487
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060930.1 Alternate T2T-CHM13v2.0

    Range
    4954549..4958695
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)