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CFAP68 cilia and flagella associated protein 68 [ Homo sapiens (human) ]

Gene ID: 64776, updated on 1-Oct-2022

Summary

Official Symbol
CFAP68provided by HGNC
Official Full Name
cilia and flagella associated protein 68provided by HGNC
Primary source
HGNC:HGNC:1163
See related
Ensembl:ENSG00000137720 AllianceGenome:HGNC:1163
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C11orf1
Summary
Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in testis (RPKM 18.8), kidney (RPKM 14.0) and 25 other tissues See more
Orthologs
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Genomic context

See CFAP68 in Genome Data Viewer
Location:
11q23.1
Exon count:
5
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (111879541..111885975)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (111889784..111896218)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (111750265..111756699)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene ALG9 alpha-1,2-mannosyltransferase Neighboring gene G protein subunit gamma 5 pseudogene 3 Neighboring gene ferredoxin-fold anticodon binding domain containing 1 Neighboring gene ribosomal protein L37a pseudogene 8 Neighboring gene HSPB2-C11orf52 readthrough (NMD candidate) Neighboring gene crystallin alpha B Neighboring gene heat shock protein family B (small) member 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ23499

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001330371.2NP_001317300.1  UPF0686 protein C11orf1 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AJ250229, AP001781, BM828345
    Consensus CDS
    CCDS81625.1
    UniProtKB/Swiss-Prot
    Q9H5F2
    UniProtKB/TrEMBL
    E9PS93
    Related
    ENSP00000435864.1, ENST00000530214.5
  2. NM_022761.3NP_073598.1  UPF0686 protein C11orf1 isoform 1

    See identical proteins and their annotated locations for NP_073598.1

    Status: VALIDATED

    Source sequence(s)
    AP001781
    Consensus CDS
    CCDS8350.1
    UniProtKB/Swiss-Prot
    Q9H5F2, Q9NQC6
    Related
    ENSP00000260276.3, ENST00000260276.8
    Conserved Domains (1) summary
    pfam06608
    Location:2149
    DUF1143; Protein of unknown function (DUF1143)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    111879541..111885975
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011542957.4XP_011541259.1  UPF0686 protein C11orf1 isoform X1

    Related
    ENSP00000432128.1, ENST00000530799.5
    Conserved Domains (1) summary
    pfam06608
    Location:32165
    DUF1143; Protein of unknown function (DUF1143)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    111889784..111896218
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)