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FHIP2B FHF complex subunit HOOK interacting protein 2B [ Homo sapiens (human) ]

Gene ID: 64760, updated on 23-Nov-2021

Summary

Official Symbol
FHIP2Bprovided by HGNC
Official Full Name
FHF complex subunit HOOK interacting protein 2Bprovided by HGNC
Primary source
HGNC:HGNC:16492
See related
Ensembl:ENSG00000158863
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
RAI16; FAM160B2
Expression
Ubiquitous expression in skin (RPKM 11.2), prostate (RPKM 9.4) and 25 other tissues See more
Orthologs
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Genomic context

See FHIP2B in Genome Data Viewer
Location:
8p21.3
Exon count:
22
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 8 NC_000008.11 (22089150..22104911)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (21946661..21962422)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene VISTA enhancer hs782 Neighboring gene fibroblast growth factor 17 Neighboring gene VISTA enhancer hs781 Neighboring gene dematin actin binding protein Neighboring gene nudix hydrolase 18 Neighboring gene HR lysine demethylase and nuclear receptor corepressor Neighboring gene HR upstream open reading frame

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ11125, FLJ21801, MGC138352

General protein information

Preferred Names
FHF complex subunit HOOK interacting protein 2B
Names
family with sequence similarity 160 member B2
protein FAM160B2
retinoic acid induced 16
retinoic acid-induced protein 16

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001354250.2NP_001341179.1  FHF complex subunit HOOK interacting protein 2B isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice junction compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is 1 aa shorter compared to isoform 1.
    Source sequence(s)
    AC091171
    Conserved Domains (1) summary
    pfam10257
    Location:79475
    RAI16-like; Retinoic acid induced 16-like protein
  2. NM_001354251.2NP_001341180.1  FHF complex subunit HOOK interacting protein 2B isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (3) is shorter at the N-terminus compared to isoform 1.
    Source sequence(s)
    AC091171
    Conserved Domains (1) summary
    pfam10257
    Location:21418
    RAI16-like; Retinoic acid induced 16-like protein
  3. NM_022749.7NP_073586.5  FHF complex subunit HOOK interacting protein 2B isoform 1

    See identical proteins and their annotated locations for NP_073586.5

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (1).
    Source sequence(s)
    AC091171
    Consensus CDS
    CCDS6021.2
    UniProtKB/Swiss-Prot
    Q86V87
    Related
    ENSP00000289921.6, ENST00000289921.8
    Conserved Domains (1) summary
    pfam10257
    Location:79476
    RAI16-like; Retinoic acid induced 16-like protein

RNA

  1. NR_148727.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC091171, BC052237, HY033313
  2. NR_148728.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC091171
  3. NR_148729.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC091171
  4. NR_148730.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC091171
  5. NR_148731.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC091171

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p13 Primary Assembly

    Range
    22089150..22104911
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006716381.3XP_006716444.1  FHF complex subunit HOOK interacting protein 2B isoform X1

    Conserved Domains (1) summary
    pfam10257
    Location:79476
    RAI16-like; Retinoic acid induced 16-like protein
  2. XM_005273602.4XP_005273659.1  FHF complex subunit HOOK interacting protein 2B isoform X3

    See identical proteins and their annotated locations for XP_005273659.1

    Conserved Domains (1) summary
    pfam10257
    Location:79476
    RAI16-like; Retinoic acid induced 16-like protein
  3. XM_017013734.1XP_016869223.1  FHF complex subunit HOOK interacting protein 2B isoform X2

    Conserved Domains (1) summary
    pfam10257
    Location:21418
    RAI16-like; Retinoic acid induced 16-like protein

RNA

  1. XR_428314.3 RNA Sequence

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